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Сибирское медицинское обозрение. 2014. № 5 View full text Количество просмотров : 9653Description Authors Annotation Keywords Reference List Comments Statistics  Malinovskaya N. A., Prokopenko S. V., Komleva Yu. K., Panina Yu. A., Pozhilenkova E. A., Ryabokon R. V., Salmina A. B. Molecular markers of glial activation
in neuroinflammation: new opportunities for pharmacotherapy of neurodegeneration. Siberian medical review. 2014; № 5: 5-15. (In Rus.). Authors Malinovskaya Natalia Alexandrovna Doctor of Medicine Sciences, Research Institute of Molecular Medicine and Patobiochemistry, Assistant Professor of the Department of Biological Chemistry with Course of Medical, Pharmaceutical and Toxicological chemistry; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; reg.kgmu@gmail.com Prokopenko Semyon Vladimirovich Dr.Med.Sc., Professor & Head of the Department of Neurological Diseases with the Course of Medical Rehabilitation; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; s.v.proc.58@mail.ru Komleva Yulia Konstantinovna Cand.Med.Sc., Associate Professor, Department of Biochemistry with courses of medical, pharmaceutical and toxicological chemistry; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; yuliakomleva@mail.ru Panina Yulia Anatol’evna Postgraduate Student and Assistant of the Department of Biological Chemistry with the Course of Medical, Pharmaceutical and Toxicological Chemistry; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; yulia.panina@list.ru Pozhilenkova Elena Anatol’evna Cand.Biol.Sc., Associate Professor of the Department of Biological Chemistry with the Course of Medical, Pharmaceutical and Toxicological Chemistry; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; elena.a.pozhilenkova@gmail.com Ryabokon’ Roman Vladimirovich Ordinator and Assistant of the Department of Anatomy and Histology; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; r-ryabokon@mail.ru Salmina Alla Borisovna PhD, Dr.Med.Sc., Professor, Head of the Department of Biological Chemistry with the Course of Medical, Pharmaceutical and Toxicological Chemistry; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; allasalmina@mail.ru Annotation The review provides information about the role of NAD+-converting enzymes (CD38, CD157) and the complex ofMAC- 1 and C3 complement component in the pathogenesis of acute and chronic neurodegeneration. The role of these molecules as potential molecular markers and targets for diagnosis and therapy of neurodegenerative diseases is discussed. Keywords: neurodegeneration, CD38, CD157, МАС-1, C3 component of complement, molecular marker, target molecule Reference List: 1. Gavrikova V.V., Masuda H., Murakami A., Hasegawa A., Koike R., Kurokha Ya., Uchiyama S. Approaches to the treatment of Parkinson's disease in Russia and Japan: AComparative Analysis //Siberian Medical Review. 2011. № 4. P. 59-62. 2. KuvachevaN.V., Morgun A. V., HilazhevaE.D., Malinovskaya N.A., Gorina Ya.V., Pozhilenkova E.A., Frolova O.V., Trufanova L.V., Martynova G.P., SalminaA.B. 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Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein // Glia. 2007. Vol. 55, № 11. P. 1178-1188. 60. Zocchi E., Usai C., Guida L., Franco L., Bruzzone S., Passalacqua M., De Flora A. Ligand-induced internalization of CD38 results in intracellular Ca2+ mobilization: role of NAD+ transport across cell membranes // FASEB J. 1999. Vol. 13. P. 273-283. Comments Visits: 22688 Description Authors Annotation Keywords Reference List Comments Statistics Kotlovskiy M. Y., Pokrovskiy A. A., Kotlovskaya O. S., Osedko A. V., Osedko O. Y., Titova N. M., Titov V. N., Kotlovskiy Y. V., Trifonova O. Y., Dygai A. M. Influence of polymorphism of OATP1B1 transporter to the pharmacokinetics and therapeutic effects of statins. Siberian medical review. 2014; № 5: 15-23. (In Rus.). Authors Kotlovskiy Mikhail Yurievich Cand.Med.Sc., the Head of Department of gasliquid, liquid-liquid and TOF mass-spectrometry; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; misha11443@rambler.ru Pokrovskiy Artemiy Alexandrovich Biologist; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; 13th_Apostol@mail.ru Kotlovskaya Ol’ga Sergeevna Deputy Head on the quality of laboratory services, Researcher, Head of PCR analysis laboratory; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; csrl@mail.ru Osedko Alexey Vladimirovich postgraduate student; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; alizz@yandex.ru Osedko Olga Yakovlevna Senior Researcher; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Osedkoolga@yandex.ru Titova Nadezhda Mitrofanovna Cand.Biol.Sc., Professor; Siberian Federal University of Ministry of Education and Science of the Russian Federation; tinami6@mail.ru Titov Vladimir Nikolaevich Dr.Med.Sc., Professor, Head of Laboratory of Clinical Biochemistry of lipid metabolism; Russian Cardiology Research and Production Complex of Ministry of health of the Russian Federation, ; vn_titov@mail.ru Kotlovskiy Yuriy Vasilievich Dr.Med.Sc., Professor, the Head of Central Science-Research Laboratory; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; office@krascnil.ru Trifonova Ol’ga Yurievna .Med.Sc., the Head of the Cardiology Department Clinic; State Establishment Scientific – Research Institute of Pharmacology named after E.D.Goldberg; mmu@pharm.tsu.ru Dygai Alexander Mikhailovich Dr.Med.Sc., Professor, the Head; State Establishment Scientific – Research Institute of Pharmacology named after E.D.Goldberg; amd@pharm.tsu.ru Annotation The importance of membrane transporters for pharmacokinetics is increasingly recognized during last ten yers. Genetic polymorphisms of transporters of drugs are related to interpersonal differences in the distribution, efficacy and toxicity of pharmaceuticals. In this scientific review are discussed the current knowledge about expression, functioning of protein 0ATP1B1 and about gene polymorphisms 0ATP1B1 influence on the efficacy and safety of statins. Keywords: 0ATP1B1, polymorphism, pharmacogenetics, statin Reference List: 1. 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J. Med. 2008. Vol. 359, № 8. P. 789-799. 45. ShikataE., Yamamoto R., Takane H., ShigemasaC, Ikeda T., Otsubo K., Ieiri I. Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin //J. Hum. Genet. 2007. Vol. 52, №2. P. 117-122. 46. Shitara Y., Horie T., SugiyamaY. Transporters as a determinant of drug clearance and tissue distribution // Eur. J. Pharm. Sci. 2006. Vol. 27, №5. P. 425-446. 47. Tirana R.G., Leake B.F., Merino G., Kim R.B. Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans // J. Biol. Chem. 2001. Vol. 276, № 38. P. 35669-35675. 48. Thompson J.F., Man M., Johnson K.J., Wood L.S., Lira M.E., Lloyd D.B., Banerjee P., Milos P.M., Myrand S.P., Paulauskis J., Milad M.A., Sasiela W.J. An association study of 43 SNPs in 16 candidate genes with atorvastatin response // Pharmacogenomics J. 2005. Vol. 5, № 6. P. 352-358. 49. 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Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22777 Description Authors Annotation Keywords Reference List Comments Statistics Verigo Y. I., Demko I. V., Petrova M. M., Sobko E. A., Mamaeva M. G. Von Willebrand factor and its role in endothelial dysfunction in coronary heart disease. Siberian medical review. 2014; № 5: 23-28. (In Rus.). Authors Verigo Y. I. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; vesna13@list.ru Demko Irina Vladimirovna Dr.Med.Sc, Professor, Head of the Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; 660022, Красноярск, ул. Партизана Железняка, 1; e-mail: demko64@ mail.ru Petrova Marina Mikhailovna MD, PhD, Prof., Head of the Department of Outpatient Therapy, Family Medicine and HL with a course of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; 660022, Красноярск, ул. Партизана Железняка, 1;тел.:8 (391)2200628; e-mail: stk99@yandex.ru Sobko Elena Albertovna Dr. Med. Sc, Assotiated Professor, Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; sobko29@mail.ru Mamaeva Marina Gennadievna Post-graduate Student, Department of Internal Diseases N 2, Doctor of the Department of Pulmonology; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; marinamamaeva101@rambler.ru Annotation The review presents an analysis of data in studying the problem of endothelial dysfunction. As a potential marker of endothelial dysfunction is considered von Willebrand factor. The importance of the correction of the endothelial dysfunction in atherosclerosis is indicated. Keywords: coronary heart disease, endothelial dysfunction, atherosclerosis, von Willebrand factor, forecast Reference List: 1. Valeyeva A.G. Serumal markers of cardiovascular risk and quality of life in patients with coronary heart disease outpatient //Perm Medical Journal. 2013 - Vol.30,№6. P.66-71. 2. VundervaldD.S., Khokhlov A.L.,TrofimovaO.V.lVundervald N.N., Kagramanyan I.N. Effect of bisoprolol and ivabradine on heart rate, the level of inflammation and endothelial dysfunction in patients with coronary artery disease: stable exertional angina //Biomedicine. 2011. №4. P.69-70. 3. Galyautdinov G.S., Chudakova E.A. Features of the hemostatic system in patients with coronary heart disease // Kazan Medical Journal. 2012. Vol. 93, № 1. P. 3-7. 4. Inzhutova A.I., Petrova M.M. Role of endothelial dysfunction in the forming and progression of cardiovascular disease //Problems of Female Health. 2011. Vol. 6, № 1. P.59-66. 5. Inzhutova A.I., Salmina A.B., Petrova M.M., Mikhutkina S.V., NarodovaV.V., Domrachev D. V. Registration of blebbing of the plasma membrane of peripheral blood lymphocytes as a rapid method of assessing the severity of patients state, complicated by hypertension forms // Bulletin SB RAMS. 2007 - Vol. 1, №123. P. 6-10. 6. Komarov A.L., Shakhmatova O.O., Stambol'sky D,V, RebrikovD.V., Kofiadi I.A., SirotkinaO.V., DeevA.D., Panchenko E.P. Risk factors of thrombotic complications and prognosis in patients with chronic ischemic heart disease // Cardiology. 2009. №11. P.4-10. 7. KratnovA.E., Piven' O.E., Kratnov A.A., Rumyantsev M.I., Matytsin S.L. The level of proinflammatory cytokines, von Willebrand factor, C-reactive protein, the metabolic activity of neutrophils and plasma antioxidant defenses in patients with coronary heart disease complicated by the development of heart failure//Immunopathology. Allergology. Infektologiya.2007. № 2. P. 34-39. 8. Lupinskaya Z. A. Vascular endothelium - the main regulator of local blood flow // Bulletin of the Kyrgyz-Russian Slavic University. 2003. № 7. P. 29. 9. Oganov R.G., Boytsov S.A. Recommendations of VNOK // Cardiovascular therapy and prevention. 2011. Vol.6, № 10, Annex 2. P. 7. 10. Oganov R.G., Maslennikova G.Ya. Epidemic of cardiovascular disease can be stopped by force of prevention // Preventive Medicine. 2009. Vol. 6, № 3. P. 3-7. 11. Parakhonskiy A.P. The immune system as a predictor of endothelial dysfunction in patients with arterial hypertension and metabolic disorders//Fundamental Researches. 2007. №9. P. 74-75. 12. Popova A.A., Berezina E.N., MayanskayaS.D. Endothelial dysfunction and the mechanisms of its formation // Siberian Medical Review. 2010. Vol. 6, № 4. P. 7-11. 13. Sobko E.A., Kraposhina A.Yu, Demko I.V., Salmina A.B. A marker of endothelial dysfunction CD-38 / ADP - ribosyl cyclase at bronchial asthma // Clinical Medicine. 2013. № 2. P. 34-38. 14. Sokolov E.I., Grishina T.I., Shtin S.R. Effect of von Willebrand factor and endothelin-1 on the formation of thrombotic status at coronary heart disease // Cardiology. 2013. Vol. 33, № 3. P. 25-30. 15. SuslinaZ.A., Tanashyan M.M., LagodaO.V. Atherosclerosis and ischemic cerebrovascular accidents // Atherothrombosis. 2009. Vol. 3, № 2. P. 60-64. 16. TanashyanM.M., SuslinaZ.A., IonovaV.G., Domashenko M.A., OrlovS.V., Chechyotkin A.O., PleshkovaM.Yu. Endothelial function state in patients with ischemic stroke of various degree of atherosclerotic carotid arteries disorders // Neurological Bulletin. 2007.Vol. 39, Is. 1. P. 12-16. 17. Tereshchenko S.N., Zhirov I.V., Malichenko E.V., Kazantseva E.E. Comparative characteristics of angiotensin inhibitors converting enzyme ramipril and enalapril in the treatment of chronic heart failure in women // Cardiology.2010. №4. P. 64-68. 18. Chernyavskaya T.K. Modem approaches to the diagnosis and correction of endothelial dysfunction in patients with arterial hypertension//Medicine. 2013. №2. P. 118-130. 19. Agewall S. Acute and stable coronary heart disease: different risk factors // Eur. Heart J. 2008. Vol. 29. P. 1927-1929. 20. Arid W.C. Endothelial biomedicine. Cambridge University Press. 2007. 1500 p. 21. Bhatt D.L., Steg P.G., Ohman E.M., Hirsch A.T., IkedaY., Mas J.L., Goto S., Liau C.S., Richard A.J., Rother J., Wilson P.W. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis //REACH Registry Investigators. 2006. Vol. 295. P. 180-189. 22. Derhasching U., Jilma B. Assesment of plateles and the endothelium in patients presenting with acute coronary syndromes - is there a future? //Thrombosis and Haemostasis.2009.Vol. 102, №6.-P.1141-1148. 23. Empana J.P., Canoui-Poitrine F.,Luc G., Juhan-Vague I., Morange P., Arveiler D., Ferrieres J., Amouyel P., Bingham A., Montaye M., Ruidavets J.-B., Haas B., Evans A., Ducimetiere P. Contribution of novel biomarkers to incident stable angina and acute coronary syndrome: the PRIME Study // European Heart Journal. 2008. Vol. 16, №29. P. 1966-1974. 24. KoprivicaZ., DjordjevicD., VuleticM., ZivkovicV., Barud- zicN., AndjelkovicN., DjuricD., Iric-CupicV., KrkeljicJ., Jakov- ljevic V. Von. Willebrand factor and Oxidative Stress parameters in Acute Coronary Syndromes // Oxidative Medicine and cellular Longevity. 2011. Vol. 2011. P. 1-11. 25. Lee K. W., Blann A. D., Lip G. Y. Inter-relationships of indices of endothelial damage/dysfunction [circulating endothelial cells, von Willebrand factor and flow-mediated dilatation] to tissue factor and interleukin-6 in acute coronary syndromes // International Journal of Cardiology. 2006. Vol. 111, № 2. P. 302-308. 26. Мое K.T., Wong P. Current trends in diagnostic biomarkers of acute coronary syndrome // Annals of the Academy of Medicine Singapore. 2010. Vol. 39, № 3. P. 210-215. 27. Starke R.D., Ferraro F., Paschalaki K.E., Dryden N.H., McKinnon T.A., Sutton R.E., Payne E.M., Haskard D.O., HughesA. D., Cutler D.F., LaffanMA, RandiA.M. Endothehal von Willebrand factor regulates angiogenesis//Blood. 2011.Vol. 117, №3.P. 1071-1080. 28. Sin D.D., Anthonisen N.R., Soriano J.B., Agusti A.G. Mortality in COPD: Role of comorbiditrs//Eur. Respur. J. 2006. Vol. 28. P. 1245-1257. 29. SmithN.L., ChenM.H., DehganA., StrachanD.P., BasuS., Soranzo N., Hayward C, Rudan I., Sabater-Lleal M., Bis J.C., de Maat M.P., Rumley A., Kong, X., Yang Q., Williams F.M., Vitart V. , Campbell H., Malarstig A., Wiggins K.L., van Duijn, C.M., McArdle W.L., PankowJ.S., Johnson A.D., SilveiraA., McKnight B., Uitterlinden A.G., Aleksic N., Meigs J.B., Peters A., Koenig W., Cushman M., Kathiresan S., Rotter J.I., Bovill E.G., HofmanA. , BoerwinkleE., ToflerG.H., PedenJ.F., PsatyB.M., LeebeekF., Folsom A.R., LarsonM.G., SpectorT.D., WrightA.F., WilsonJ.F., Hamsten A., LumleyT., Witteman J.C., Tang W., O'Donnell C.J. Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium // Circulation. 2010. Vol. 121.P. 1382-1392. 30. Spiel A.O., J.C.Gilbert, BJilma. Von Willebrand factor in Cardiovascular Disease. Focus on Acute Coronary Syndromes //Circulation. 2008. Vol. 117,№ 11. P. 1449-1459. 31. Tedgui A., Mallat Z. Anti-inflammatory mechanisms in the vascular wall//Circulation Research. 2001. Vol. 88. P. 877-887. 32. Tkac J., Man P.S.F., Sin D.S. Systemic conseguences of COPD // Ther. Respur. Dis. 2007. Vol. 1. P. 47-59. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22764 Description Authors Annotation Keywords Reference List Comments Statistics Shul'min A. V., Dobretsova E. A., Burgart Yu. V., Keush V. M. Medical and social features of young family in contemporary conditions. Siberian medical review. 2014; № 5: 28-35. (In Rus.). Authors Shul'min Audrey Vladimirovich Candidate of Medical Sciences, Associate Professor, Head of Department of Public Health and Health Care; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; аndreyshumn@gmail.com Dobretsova Elena Aleksandrovna Cand.Med.Sc., Senior Research Fellow of the Department of Public Health and Health Care with the course of Social Work; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; eldobretsova@gmail.com Burgart Yuriy Vladimirovich ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; infinity@mail.ru Keush Viktor Mikhaylovich ; Divnogorsk Interregional Hospital, Krasnoyarsk Territory; Dcgb@mail.ru Annotation The article is a review of the scientific literature about medical and social features of young family in the contemporary conditions. The main problems of this category of the population in the terms of the transformation the family institution as a whole are presented. The particularities of marriage rate in Russia and abroad are given. Keywords: young family, marriage rate, medical and social features of a young family Reference List: 1. Anafyanova T.V. To the guestion of the development strategy of the health potential in young families // Contemporary Problems of Science and Education. 2011. №5. P. 130-135. 2. Antonov A.I., Borisov V.A. Dynamics of the Russian population in the XXI century and demographic policy priorities. M.: Klyuch-C, 2006. P. 57. 3. Artyomenko V.V., Shabunova A. A. Influence of social and economic characteristics of the family to the children's health // The Problems of the Territory Development. 2009. Is. 2. P. 68-77. 4. ArtyukhovI.P., Anafyanova T.V., NovikovO.M., Kapitonov V.F., Pavlov A.V. Family Medicine. Health of young families; Krasnoyarsk Medical University. 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Young family: problems and prospects of the social support // Bulletin of the Eastern Economics and Law Humanitarian University. 2010. №4. P. 119-124. 12. Golod S.I. Sociological-demographic analysis of the state and evolution of the family // Sociological Research. 2008. № 1. P. 40-49. 13. Denisov I.N. Development of family medicine-the basis of the reorganization of primary health care of the population in the Russian Federation//Health Care. 2010. №5. P. 151-164. 14. Dobrokhleb V.G., Belobragin N.V. Reproductive orientation of the students // Bulletin of the Russian State Humanitarian University. 2010. №6. P. 15-22. 15. Dolbik-Vorobey T.A. Student youth about the problems of marriage and childbirth // Sociological Research. 2003. №11. P. 78-83. 16. EfimovS.G. Modern aspects ofwell-being and ill-being of the modem family in the Republic of Buryatia // Bulletin of the Buryat State University. 2011. №5. P. 248-253. 17. Zhil'tsova E.E., Konovalov O.E. Informing of the students about the prevention of sexually transmitted infections // Problems of Social Hygiene, Health and History of the Medicine. 2012. №6. P. 17-19. 18. Ibragimov M.-R. A. Ethnic and demographic aspects of Dagestan family development in the twentieth century// Bulletin of the Institute IAE. 2011. №1. P.53-65. 19. Katznelson G.S. Features of the processes of birth, death and marriage of the rural population of the Orenburg region at the frontier XX - XXI centuries // Bulletin OGPU. 2007. №1. P.21-26. 20. Korchagina P.S., KalachikovaO.N. Self-preserving behavior as a factor of forming the health of the population // Problems of the Territorial Development. 2013. №2. P.2-12. 21. Kuz'menko T.V. Reproductive plans of young married couples: the influence of the older generation // Bulletin of the Nizhny Novgorod University named after N.I. Lobachevsky. 2010. №4. P.60-67. 22. Leschenko Ya.A., Boeva A.V. Features and trends of processes of marriage and divorce in the Eastern Siberia //Bulletin ofBuryat State University. 2010. № 14. P. 177-180. 23. Medvedeva N.A. Evaluation of marriages and divorces in the Vologda region // Milk Industry Bulletin. 2012. №3. P.93-99. 24. Mezeneva M. V. Poverty of young families: strategies and features of overcoming (in Vologda region) // Bulletin of St. Petersburg State University. 2011. №4. P. 390-398. 25. Mikhailova K.S. The transformation of the marriage institution in the Far East of Russia // Power and Control in the East of Russia. 2008. № 3. P. 248-257. 26. The population of Russia 2010-2011. Eighteenth to nineteenth annual demographic report / Executive Editor A.G. Vishnevsky. M.: Publishing House House of GU VShE, 2013. 530 p. 27. Novikov O.M., Artyukhov I.P., Kapitonov V.F. et al. Medical and demographic problems of different types of families, living in rural areas // Sib. Med. Review. 2007. № 4. P. 78-81. 28. Nurmatova Z.I., Nurmatov A.A., Yusupova M.R. Youth and their reproductive health // Scientific and Practical Journal TIPPMK. 2012. №2. P. 29-31. 29. Panfilova T.N., Medvedeva O.V. Regional aspects of the implementation of family policy // Problems of Soc. Hygiene and History of Medicine. 2010. №2. P.42-47. 30. Popova D.O. Transformation of family values and the second demographic transition in Russia: who is at the vanguard ? [Electronic resource], - Mode of access: http://www.demoscope. ru/weekly/2010/0423/analit01.php. 31. Popova I.P. Behavior regarding health and financial status: gender aspects (according to a longitudinal survey) // Health Rus. Federation. 2007. № 1. P. 47-50. 32. Rostovskaya T.K. Development of the Institute of young family in contemporary society // State Counselor. 2013. №2. P. 46-52. 33. Smirnova N.N. Development trends of modem urban young family // Historical, Philosophical, Political and Legal Sciences, Cultural Studies and Art Criticism. Problems of Theory and Practice. 2013. №2-1. P. 178-181. 34. Sofronova T.G. Features and trends of marriage in Russia // Initiatives of the XXI century. 2010. № 3. P. 53-55. 35. Soultanaeva Z.M., Gurova Z.G., Galimov Sh.N. Age aspects of marriage and divorce in the Republic of Bashkortostan //Problems of Reproduction. 2011. №6. P.9-13. 36. SurmachM.Yu. Reproductive behavior ofyouth in Belarus and its determination // Journal of Grodno State Medical University. 2011. №4. P. 32-35. 37. Tataurova E.A., Novoselov V.P., Ponich E.S. et al. Sociological evaluation of formation the reproductive plans of youth // Siberian Medical Journal. 2009. № 3. P. 57-60. 38. Udaltsova M.V., Nosova N.S. Young family as the object of social policy// Omsk Scientific Bulliten. 2010. №3. P.73-75. 39. FadeevaN.L. Marriage and family structure in the context of the demographic situation // Scientific Notes of Petrozavodsk State University. Series: Social and Humanitarian Sciences. 2013. №3. P.50-53. 40. Fadeeva N.L. Features of state policy regarding young family: the solution of housing problems on the example of the Republic of Karelia // Scientific Notes of Petrozavodsk State University. Series: Social and Humanitarian Sciences. 2012.№1.-P. 105-108. 41. HasanovaR.R. Self-preservation behavior of the population as a factor of life expectancy // Population Health and the Environment. 2013. №5. P.43-46. 42. Khachatryan L.A. Modern marriage - a result of the evolution of family and marriage relations // Bulletin of Perm University. 2011. Issue 1. P. 89-100. 43. Tsinchenko G.M. Social policy regarding young family //Management Consulting. 2010. №3. P. 180-187. 44. Tsitkilov P.Ya. Material and housing disadvantage as a priority problem of the Russian young family and approaches to its solving in social practice // Domestic Journal of Social Work. 2012. №3. P. 154-161. 45. Chernov A. V. Konovalov O.E., Shevlyakova T.V. Medical and social characteristics of women of reproductive age and their families // Problems of Social Hygiene, Health and History of Medicine. 2012. № 1. P. 23-25. 46. Chernova Zh. V. «Demographic Reserve»: a young family as an object of state policy // Woman in Russian society. 2010. №2. P.26-38. 47. Shingarkina D.A. The study of concepts of today's students about marriage // Vector of Science of Tolyatti State University. 2012. №2. P. 188-193.48. Agha S. Changes in the timing of sexual initiation among young Muslim and Christian women in Nigeria // Arch. Sex Behav. 2009. Vol. 38, № 6. P. 899-908. 49. Bruderl J., Diekmann A. Education, birth cohort, and marriage age: a comparative analysis of marriage age in West Germany, East Germany, and the United States // Z. Soziol. 1994. Vol. 23,№1. P.56-73. 50. Carmichael G. A., Whittaker A. Choice and circumstance: qualitative insights into contemporary childlessness in Australia // Eur. J. Population. 2007. Vol. 23, № 2. P. 111-143. 51. ColonM., Martinez R., TullaM., PerezJ., SantaellaY., LarasL. Psychosocial factors associated with failure to use contraception among adolescents with repeat pregnancies in Puerto Rico // Bol. Asoc. Med. P. R. 2014. Vol. 106, № 1. P. 12-16. 52. Dillender M. The death of marriage? The effects of new forms of legal recognition on marriagerates in the United States //Demography. 2014. Vol. 51, №2. P. 563-585. 53. Dye J. L. Fertility of American Women: 2006 : Current Population Reports - Washington : U. S. Census Bureau,2008. P. 20-558. 54. Gavalas V. S. Family formation and dissolution in an Aegean island // J. Biosoc. Sci. 2005. Vol. 37, № 3. P. 351-370. 55. Ghilagaber G., Shusheng L., Johansson A. Changes in marriage age and first birth interval in Huaning County // Southeast Asian J. Trap. Med. Public Health. 2005. Vol. 36, №5. P. 1329-1338. 56. Holland J. A., de ValkH. A. Ideal ages for family formation among immigrants in Europe // Adv. Life Course Res. 2013. Vol. 18, №4. 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Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22803 Razmakhnin E.V., Konovalova O.G. OCTANOIC ACID IN THE TREATMENT OF CHOLELITHIASIS (EXPERIMENTAL RESEARCH) Pages: 36-40  Description Authors Annotation Keywords Reference List Comments Statistics Razmakhnin E. V., Konovalova O. G. Octanoic acid in the treatment of cholelithiasis (experimental research). Siberian Medical Review. 2014; № 5: 36-40. (In Rus.). Authors Razmakhnin E. V. ; Chita State Medical Academy; e.iazmakhnin@mail.ru Konovalova O. G. ; Chita State Medical Academy; konoraIoraoIgagen@yandex.ru Annotation The aim of the research. Experimentally justify the use of octanoic acid for litholysis of gallstones. Materials and methods. In the experiments in vitro 103 gallstones of different composition were used. In the experiment in vivo 40 adult rabbits: after modeling of cholelithiasis on the third day after operation through cholecystostoma a solventwas injected, outcome was assessed at 3,5, 7,14 days after treatment. Results. Average time of dissolution the stones was 5,63 ± 2,10 min, counting on 1 mg of the stone weight, solubility is inversely proportional to the degree of mineralization of stones. A mixture of octanoic acid and glycerol in a ratio of 1:1 does not change the solubility. In vivo complete dissolution was achieved by the 4th day of treatment, toxic effects haven't been identif ied. Conclusion. Octanoic acid is active to all types of gallstones, has low toxicity in a dose required to dissolve stones. Keywords: cholelithiasis, octanoic acid, litholysis, litholytic mixture Reference List: 1. Gerasimov A.N. Medical statistics. M.: Medical Information Agency, 2007. 480 p. 2. Milonov O.B., Gureeva H.V. Contemporary aspects of the dissolution of gallstones//Surgery. 1984. №7. P. 144-150. 3. Rabichev E.O., Durov V.A., Shakhparonov M.I. About the structure and physico-chemical properties of solutions of glycerol // Bulletin MSU. Chemistry. 1980. Vol. 21, № 1. P. 37-42. 4. RazmahninE.V., LobanovS.L., KonovalovaO.G. Possibility of atomic-emission analysis in the study of the composition of gallstones //Bulletin of Buryat State University. 2013. № 13. P. 133-137. 5. Ryzhkova O.V., Saifutdinov R.G. Chemical dissolution of gallstones // Public Health and Health Care. 2005. № 1-2. P. 172-175. 6. Thai S.V., Zakharov V.V., Rusanov V.M. Albumin - the best selling drug of the blood in transfusion practice // Bulletin of Blood Care of Russia. 2012. №3. P.40-45. 7. Khertek Sh.B. The variants of correction obstructive jaundice in urqent surqery // Siberian Medical Review. 2012. №3. P. 6-10. 8. Allen M.J. Rapid dissolution of gallstones by methyl-tert- buthyl-ether // N.Engl.J.Med. 1985. Vol.312. P.217-220. 9. Wada H., Shintani D., Ohlrogge J. Why do mitochondria synthesize fatty acids? Evidence for involvement in lipoic production// PNAS - 1997 - Vol. 94 - P. 1591-1597. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22784 Description Authors Annotation Keywords Reference List Comments Statistics Ratkin A. V., Kaidash O. A., Pfarger Y. A., Ivanov V. V., Adekenov S. M., Ryazantseva N. V., Chuchalin V.S., Vengerovskiy A. I. Hypolipidemic influence of sesquiterpene lactones arglabin and achillin to the models of acute hyperlipidemia. Siberian medical review. 2014; № 5: 40-43. (In Rus.). Authors Rat'kin Alexander Valentinovich Cand. Pharm.Sci., Associate Professor, Department of Pharmaceutical Technology; Siberian State Medical University; iatkin@ssmu.ru Kaidash Olga Alexandrovna Post-graduate Student, Department of pharmacology; Siberian State Medical University; Pfarger Yuliya Andreevna Post-graduate Student, Department of Pathophysiology; Siberian State Medical University; ipfarger@gmail.com Ivanov Vladimir Vladimirovich Cand.Med.Sci., Associate Professor, Head of the Laboratory of Biological Models; Siberian State Medical University; ivanovwl953@gmail.com Adekenov Sergazy Mynzhasarovich Dr. Chem.Sci., Academician of NAS RK.Cchairman of the board of JSC «International scientific-industrial holding Phytochemistry»(Karaganda, Kazakhstan); JSC «International scientific-industrial holding Phytochemistry»(Karaganda, Kazakhstan); arglabin@phyto.kz Ryazantseva N. V. ; State Educational Institution of Higher Professional Education "Siberian State Medical University" of the Ministry of Health of the Russian Federation, Tomsk; nv_ryazan@mail.ru Chuchalin Vladimir Sergeevich Dr. Pharm.Sci., Dean of the Faculty of Pharmacy; Siberian State Medical University; phtech@ssmu.ru Vengerovskiy Alexander Isaacovich Dr.Med.Sci., Head of Department of Pharmacology, Professor; Siberian State Medical University; phtech@ssmu.ru Annotation The aim of the research. To study hypolipidemic properties of sesquiterpene lactones arglabin and achillin at the model of acute hyperlipidemia caused by ethanol in rats. Materials and methods. Hyperlipidemia in rats was induced by a single intragastric injection of 40% ethanol at a dose of 5 g / kg (based on absolute ethanol). Arglabin and achillin in dose 10 mg/kg was injected intragastric during 7days before injection of ethanol. In the blood serum was measured the content of triacylglycerides, free fatty acids, total cholesterol, cholesterol in lipoproteins of low and high density, atherogenic index. Results. Sesquiterpene lactones arglabin and achillin decreased in serum of rats increased content of triacylglycerides, free fatty acids and cholesterol in low density lipoproteins at the acute hyperlipidemia, caused by single injection of ethanol. Conclusion. The data indicates the hypolipidemic activity of the studied lactones. Keywords: experimental hyperlipidemia, ethanol, arglabin, achillin, nicotinic acid Reference List: 1. Arabidze G.G. Clinical immunology of atherosclerosis -from therapy to practice//Atherosclerosisand Dyslipidemia. 2013. №1. P.4-19. 2. Vengerovskiy A.I. Pharmacology: lectures course (4th ed., Rev. and Ex,). M .:GEOTAR-Media,2012. P.589-603. 3. Kagarlitskiy A.D., Adekenov S.M., Kupriyanov AN. Sesquiterpene lactones of plants in Central Kazakhstan. Alma-Ata, Nauka, 1987. 240 p. 4. Konovalov G.A., Zvezdkin P.V., Hayutina I.V., Filonenko I.V., Askopyan V.S., Karneeva O.V., Doroshchenko A.D., Kurganskaya T.S. Hypolipidemic therapy and reoferez at dislipoproteidemia. // Consilium medicum. 2003. Vol. 5, № 11. P. 609-614. 5. Rat'kin A.V., Arystan L.I., Yakovleva Yu.A., Ivanov V.V., Ryazantseva N.V., Chuchalin V.S., Adekenov S.M. Influence of leukomizine sesquiterpene y-lactone to the triacylglycerols level in experimental model of hyperlipidemia in rat hepatoma cells //Siberian Medical Review. 2014. № 1. P.44-48. 6. Rodnova E.A., Ivanov V.V., Ledyukova S.I., Chuchalin V.S., Rat'kin A.V., Rakhimova B.B., Habarov I.A., Adekenov S.M. Hypolipidemic effect of leukomizin to the models of acute hyperlipidemia, induced by ethanol // Bulletin of Siberian Medicine. 2013 - Vol. 12, № 1. P. 43-48. 7. Guidelines for pre-clinical study of medicinal products. Part 1 / Ed. A.I. Mironov. M.: Grif and K, 2013 - 944 p. 8. Arun Sam Lai A., Kumar T., Balakrishna Murthy P., Sadasivan Pillai K. Hypolipidemic effect of Coriandrum sativum L. in triton-induced hyperlipidemic rats// Ind. J. Exp. Biol. 2004. Vol. 42, №9. P.909-912. 9. Bodor E.T., Offermanns S. Nicotinic acid: an old drug with a promising future//Br. J. Pharmacol. 2008. Vol. 153, № 1. P. 68-75. 10. Chaturvedi D. Sesquiterpene lactones: Structural diversity and their biological activities//Res. Signpost. 2011. Vol. 1, № 1. P. 313-344. 11. Shukla S.D., Sun G.Y., Gibson Wood W., Savolainen M.J., Ailing C., Hoek J.B. Ethanol and lipid metabolic signaling // Ale. Clin. Exp. Res. 2001. Vol. 25, № 1. P. 33-39. 12. Yao P., Song F., Li K., Zhou S., Liu S., Sun X., Nussler A.K., Liu L. Ginkgo biloba extract prevents ethanol induced dyslipidemia // Am. J. Chin. Med. Vol. 35, №4. P. 643-652. 13. You M., Fischer M., Deeg M.A., Crabb D.W. Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binging protein (SREBP) //J. Biol. Chem. 2002. Vol. 277, №24 - P. 29342-29347. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22774 Description Authors Annotation Keywords Reference List Comments Statistics Bagadaeva L. Y., Orlova G. M. Absence of the dynamics QT interval dispersion as a risk factor in patients with acute myocardial infarction after reperfusion.Siberian medical review. 2014; № 5: 44-47. (In Rus.). Authors Bagadaeva E. Yu. ; Irkutsk State Medical University; vilya25@mail.ru Orlova Galina Mikhailovna Dr.Med.Sc., Professor, the Head of the Department of Hospital Therapy; Irkutsk State Medical University, Ministry of Health of the Russian Federation; vicgal@yandex.ru Annotation The aim of the research. Identification of risk factors associated with a lack of dynamics QT interval dispersion after reperfusion of coronary artery in patients with acute myocardial infarction. Materials and methods. QT interval dispersion was calculated before and 1 hour after reperfusion of the coronary artery in patients with acute myocardial infarction. All patients were divided into 2 groups: with reduced dispersion QT (n = 50) and without reduction (n = 45). Results. Dilation of the left ventricle increased the risk of absence of reduction QTcd after reperfusion in 1.94 times: OR 1.94(1,34- 2,79], p = 0.013. Inpatients with reduced left ventricular systolic function to reduce the risk of lack QTcd after reperfusion during 1 hour increased by 1.65 times; OR 1.65(1,1-2,4], p = 0.035 Conclusion. Dilation of the left ventricle is an independent factor of the absence of reducing QTcd after coronary artery reperfusion Keywords: acute myocardial infarction, the dispersion of the interval QT, coronary angioplasty Reference List: 1. Bemshtein L.L., Novikov V.I., Grishkin Yu.N. Evaluating of the reperfusion effectiveness at acute myocardial infarction: contemporary concepts and methods // Russian Journal of Cardiology. 2005. № 1. P. 73-79. 2. Boldueva S.A., Burak T.Ya., Zhuk V.S., Leonova I.A., Samokhvalova M.V. To the problem of QT interval dispersion in patients with acute myocardial infarction // Russian Journal of Cardiology. 2001. №2. P. 14-17. 3. Radzevich A.E., Uranova E.V., Bulanova A.A., Popov V.V. Influrnce of percutaneous transluminal coronary angioplasty on left ventricular function, the parameters of a high-resolution ECG, QT interval dispersion and heart rate variability // Thoracic and Cardiovascular Surgery. 2006. № 4. P.23-29. 4. Bonnemeier Н, Hartmann F, Wiegand UK, Bode F, Katus HA, Richardt G. Course and prognostic implications of QT interval and QT interval variability after primary coronary angioplasty in acute myocardial infarction //J. Am. Coll. Cardiol. 2001. Vol. 37. P. 44-50. 5. LopesN.H., GrupiC, Cleberson H. Dina, Accio FT de Gois, Hajjar L, Ayub B, Rochitte C.E, Ramires J.F, Kalil Roberto, Hueb W. QT interval dispersion analysis in acute myocardial inlarction (AMI) patients: coronary reperfusion effect // Arquivos Brasileiros de Cardiologia. 2006. Vol. 87. P. 91-98. 6. Malik M., Velislav N, Batchvarov. Measurement, interpretation and clinical potential of QT dispersion //Journal of the American College of Cardiology. 2000. Vol. 36, №6. P. 1749-1766. 7. Moller J.E., Husic M., Sondergaard E. Poulsen S., Egstrup K. Relation of early changes of Q-T dispersion to changes in left ventricular systolic and diastolic function after a first acute myocardial infarction // Scand. Cardiovasc. J. 2002. Vol.36,№5. P.259-261. 8. Padmanabhan S., Silvet H., Amin J., Pai R. G. Prognostic value of QT interval and QT dispersion in patients with left ventricular systolic dysfunction: Results from a cohort of 2265 patients with an ejection fraction of <40% Original Research Article //American Heart Journal. 2003. Vol. 145, №1. P. 132-138. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22797 Description Authors Annotation Keywords Reference List Comments Statistics Demko I. V., Sobko E. A., Chubarova S. V., Soloveva I. A., Kraposhina A. Yu., Medvedeva N. N., Vakhtina L. Yu., Zhukov E. L., Ishchenko О. P., Zhegalov P. S. Features of the systemic inflammation, external respiration functions and morphological structure of the Bronchial mucous membrane in severe bronchial asthma. Siberian medical review. 2014; № 5 : 47-52. (In Rus.). Authors Demko Irina Vladimirovna Dr.Med.Sc, Professor, Head of the Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; 660022, Красноярск, ул. Партизана Железняка, 1; e-mail: demko64@ mail.ru Sobko Elena Albertovna Dr. Med. Sc, Assotiated Professor, Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; sobko29@mail.ru Chubarova Svetlana Vladimirovna Cand.Med.Sc, Assistant of the Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; svetachubarova@mail.ru Solovjeva Irina Anatolyevna Cand.Med.Sc, Assistant, Department of Internal Diseases N2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; solovieva.irina@inbox.ru Kraposhina Angelina Yurievna Cand.Med.Sc, Assistant of the Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; angelina-maria@inbox.ru Medvedeva Nadezhda Nikolaevna Dr.Med.Sc., Professor, the Head of the Department of Anatomy and Histology; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; medvenad@mail.ru Vakhtina L. Yu. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; vak-lar@mail.ru Zhukov E. L. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; evgen_patolog@mail.ru Ishchenko Olga Petrovna Cand.Med.Sc.,; Krasnoyarsk regional hospital (Krasnoyarsk); fridag@yandex.ru Zhegalov P. S. ; Krasnoyarsk regional hospital (Krasnoyarsk); gs7@mail.ru Annotation The aim of the research. To study the morphological changes of the bronchial mucosa membrane in interconnection with indicators of systemic inflammation and respiratory function in patients with severe bronchial asthma (BA). Materials and methods. The study involved 35 patients of both sexes with severe asthma. The control group consisted of 40 healthy volunteers. At all patients were examined the respiratory function, to determine the level of cytokines TNF-a, IL-4, IL-2, IL-6, IL-10, INF-y, C-reactive protein, bronchoscopy, histological methods. Results. Were received high levels of proinflammatory cytokines, CRP in patients with asthma. Were shown the features of the implementation of the immune response, depending on the form of the disease. Was confirmed the role of macrophages in the development of inflammation at asthma. Conclusion. There are specific morphological markers of structural changes in the bronchial wall, depending on the form of the disease. Keywords: asthma, bronchial mucosa membrane, BRUSH-biopsy, inflammation Reference List: 1. Avtandilov G.G. Diagnostic medical ploidometriya.M. : Medicine, 2006 - 192p. 2. Global strategy for the diagnosis, treatment and prevention of chronic obstructive pulmonary disease (revision 2011): Transl. from English. / Ed. A. Belevsky. M.: Russian Respiratory Society, 2012 - 80 p. 3. Kozlova O.S., Zhestko A.B., Kulagin V.V. Bronchial asthma in combination with allergic rhinitis: clinical and functional, immunological features // Pulmonology. 2011. № 1. P.70-73. 4. LandyshevYu.S., SurovA.V., Lazutkina E.L., Georgievskiy N.I., Tseluyko S.S., Georgievskaya M.N. The role of cytokines and polymorphonuclear neutrophils in the pathogenesis of asthma // Far East Medical Journal. 2008. № 2. P. 134-138. 5. Solovyova I.A., Sobko Е.А., Kraposhina A.Yu, Ryazanova N.G., Demko I.V. Structural and functional state of the right ventricle myocardium in patients with asthma of moderate and severe degree // Siberian Medical Review. 2014. № 2. P. 42-47 6. Chuchalin A.G., Ogorodova L.M., Petrovsky F.I., Zhest- kov A.V., Il'kovich M.M., Martynenko T.I., Rebrov A.P., Reutova L.Yu., Tereshchenko Yu.A., Fassakhov R.S., Chernyak B.A. Monitoring and treatment of severe asthma in adults. Results of the national multicenter study NABAT // Therapeutic Archives. 2005. № 3. P. 36-43. 7. Bradding P. Asthma: Eosinophil Disease, Mast Cell Disease, or Both? // Allergy, Asthma & Clinical Immunology. 2008. Vol. 4. P. 84-90. 8. Hanania N. Targeting airway inflammation in asthma: current and future targets and therapies // Chest. 2008. Vol. 6, № 3. P. 245-252. 9. Meyer N., Nuss S.J., Rothe T., Siebenhuner A., Akdis C.A., Menz G. Differential serum protein markers and the clinical severity of asthma // J. Asthma Allergy. 2014. Vol. 25, № 7. P. 67-75. 10. Reuter S., Heinz A., Sieren M., Wiewrodt R., Gelfand E.W., Stassen M., Buhl R., Taube C. Mast cell-derived tumor necrosis factor is essential for allergic airway disease // Eur. Respir. J. 2008. Vol. 31, № 4. P. 773-782. 11. Wood L.G., Baines K.J., Fu J., Scott H.A., Gibson P.G. The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma // Chest. 2012. Vol. 142,№1. P.86-93. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22816 Description Authors Annotation Keywords Reference List Comments Statistics Savchenko A. A., Dresvjankina L. V., Grinshtejn Yu. I., Aristov A. I. Features of chemiluminescent activity of blood neutrophils and sputum of patients with community-acquired pneumonia during the treatment. Siberian medical review. 2014; № 5: 52-57. (In Rus.). Authors Savchenko Andrey Anatolievich Dr. Med.Sc, Professor, Head of the Department of Physiology named after Prof. A.T. Pshonik; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; aasavchenko@yandex.ru Dresvyankina Lyubov' Viktorovna Postgraduate Student, Laboratory of Molecular-Cell Physiology and Pathology; FGBNU "Research Institute of Medical Problems of the North"; immune@impn.ru Grinshtein Yuriy Isaevich Dr.Med.Sc. , Professor, Head of the Department of Therapy PE; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; grinstein.yi@gmail.com Aristov Alexander Ivanovich Assistant, the Department of Therapy PE; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; aiaristov@yandex.ru Annotation The aim of the research. A comparative study of the chemiluminescent activity of blood neutrophilic granulocytes and sputum in patients with community-acquired pneumonia of moderate severity. Materials and methods. Were examined 48 patients with community-acquired pneumonia of moderate severity, and 112 healthy people. Were studied lyutsigenin- and luminol-dependent chemiluminescence of neutrophils. Results. In patients with pneumonia within 2 weeks of antibiotic therapy is still a high level of chemiluminescence of blood neutrophils, but with a tendency to normalization of activity from the 7th day of treatment. Sputum neutrophils are characterized by low levels of chemiluminescence. Conclusion. Low sputum neutrophil chemiluminescence associated with the depletion of metabolic reserves of cells in the lung on the background of antibiotic therapy that can cause disease recurrence. Keywords: pneumonia, neutrophils, chemiluminescence, active oxygen species Reference List: 1. Vladimirov Yu.A., Proskurina E.V. Free radicals and cell chemiluminescence // Successes of Biological Chemistry. 2009 - Vol. 49. P. 341-388. 2. Dvoretskiy L.I. Community-acquired pneumonia: diagnosis and antibiotic therapy // Consilium Medicum. 2008. № 3. P. 25-30. 3. Morbidity of the population of Russia in 2010: statistical material. Part III. M., 2011. 152 p. 4. Kolenchukova O.A., Savchenko A.A., Smirnova S.V. Features of luminol- and lucigenin-dependent chemiluminescence of neutrophilic granulocytes in patients with chronic rhinosinusitis // Medical Immunology. 2010. Vol. 12, № 4-5. P. 437-440. 5. KurtasovaL.M., Savchenko A. A., EAShkapovaE.A. Clinical aspects of functional disorders of neutrophil granulocytes in cancer pathology. Novosibirsk: Nauka, 2009ю. 184 p. 6. Savchenko A.A., Zdzitovetsky D.E., Borisov A.G., Luzan N. A. Chemiluminescent activity of neutrophils and concentration level of cytokines in patients with advanced purulent peritonitis // Cytokines and Inflammation. 2013. Vol. 12, № 1-2. P. 115-119. 7. Sinopalnikov A.I., Kozlov R.S. Community-acquired respiratory tract infections: a guide for physicians. M.: Premier MT, Our Town, 2007. 353 p. 8. Chuchalin A.G., Sinopalnikov A.I. Kozlov R.S., Tyurin I.E., Rachina S.A. Community-acquired pneumonia in adults: recommendations for diagnosis, treatment and prevention: A guide for physicians. M, 2010 - 54 p. 9. Shimohina N.Yu., Savchenko A.A., Petrova М.М., Lyashenko A.A., Chizhikova I.K., Voronkovskaya A.V. Features of the hemostatic system and chemiluminescent activity of neutrophilic granulocytes in patients with acute coronary syndrome//Siberian Medical Review. 2012. №6. P.21-24. 10. Benbarek H., Ayad A., Deby-Dupont G., Boukraa L., Serteyn D. Modulatory effects of non-steroidal anti-inflammatory drugs on the luminol and lucigenin amplified chemiluminescence of equine neutrophils // Vet. Res. Commun. 2012. Vol. 36, №1.P. 29-33. 11. Fernandez E. Predictors of health decline in older adults with pneumonia: findings from the Community-Acquired Pneumonia Impact Study//BMC Geriatrics. 2010. Vol. 10, №1. P. 1-21. 12. Genestet C., Le Gouellec A., Chaker H., Polack B., Guery B., Toussaint B., Stasia M.J. Scavenging of reactive oxygen species by tryptophan metabolites helps Pseudomonas aeruginosa escape neutrophil killing // Free Radic. Biol. Med. 2014. Vol. 73.P.400-410. 13. Khan P., Idrees D., Moxley M.A., Corbett J.A., Ahmad F., von Figura G., Sly W.S., Waheed A., Hassan M.I. Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses // Appl. Biochem. Biotechnol. 2014. Vol. 173, № 2. P. 333-355. 14. Liu G., Yang H., Chen X., Wang X., Chu Y. Modulation of neutrophil development and homeostasis// Curr. Mol. Med. 2013.Vol. 13, №8.P.1270-1283. 15. Strydom N., Rankin S.M. Regulation of circulating neutrophil numbers under homeostasis and in disease // J. Innate Immun. 2013. Vol. 5, №4. P. 304-314. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22770 Description Authors Annotation Keywords Reference List Comments Statistics Antsiferova E. V., Nikulina S. Yu., Emilyanchik E. Yu., Chernova A. A., Antsiferova L. N., Maksimov V. N., Kirillova E. P., Ivanitskii E. A., Cherkashina T. V., Kachanova T. V. Role of connexin 40 gene polymorphisms in the development of idiopathic sick sinus syndrome in children. Siberian medical review. 2014; № 5: 57-62. (In Rus.). Authors Antsiferova E. V. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; aRcifeiova_ekate@mail.ru Nikulina Svetlana Yurievna Dr.Med.Sc., Professor, Head of Department of Internal Diseases №1, Vice Rector for Academic Affairs; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; nicoulina@mail.ru Emelyanchik Elena Yurievna Dr.Med.Sc., Professor of the Pediatric Department IPE; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; lenacor@mail.ru Chernova Anna Alexandrovna Cand. Med. Sci. Associate Professor of the Department of Internal Diseases № 1; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; anechkachernova@yandex.ru Antciferora Ludmila Nicolaerna Head of Children Cardiology Office; Krasnoyarsk Regional Clinical Center of the Protection of the Maternal and Childhood; anciferora_lydmila@mail.ru Maksimov Vladimir Nikolaevich Dr.Med.Sc. Associate Professort; Head of the Laboratory of Molecular genetic studies of internal diseases; Novosibirsk State Medical University; Research Institute of Therapy of the Russian Academy of Medical Science; medik11@mail.ru Kirillora Ekaterina Petrorna Dr.Med.Sc., Assistant Professor of Pediatric Department IPE; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; lenacor@mail.ru Ivanitskii E. A. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; edwiner@yandex.iu Cherkashina Tatyana Victorovna Cardiologist in the Children Cardiology Office; Krasnoyarsk Regional Clinical Center of the Protection of the Maternal and Childhood; cherkashina_tat@mail.ru Kachanova T. V. ; Krasnoyarsk Regional Clinical Children's Hospital; tany-fokina@yandex.ru Annotation The aim of the research. To study the frequency of polymorphic allelic variants of the gene connexin 40 (CX40) in children with idiopathic sick sinus syndrome. Materials and Methods. A molecular genetic study of 50 children with idiopathic sick sinus syndrome (SSS) and in 102 healthy children of the control group was conducted. Results. Association SSS with Cx40 gene polymorphisms was established. In children with idiopathic SSS was revealed statistically the significant predominance of homozygous genotype -44AA. Conclusion. The genotype -44AA gene Cx40 defines a high relative risk of developing the disorders of impulse conduction in the formation of the combined pathology of the cardiac conducting system. Keywords: children, sick sinus syndrome (SSS), bradycardia, cardiac arrhythmias, gene connexin 40 (Cx40), rs35594137, a single nucleotide polymorphism (SNP) Reference List: 1. Nikulina S.Yu., Chernova A.A., Shulman V.A., Kukushkina T.S., Voevoda M.I., Maksimov V.N. Connexin 40 gene polymorphism in the pathogenesis of hereditary sick sinus syndrome//Siberian Medical Review. 2011. №3. P. 14-19. 2. Shkol'nikova M.A. Diagnosis and treatment of life- threatening heart rhythm disorders in childhood. M.:Capital Business, 2001 - 86 p. 3. Beauchamp Р., Yamada К.А., Baertschi A.J., Green К., KanterE.M., Saffitz J.E., Kleber A.G. Relative contributions of connexins 40 and 43 to atrial impulse propagation in synthetic strands of neonatal and fetal murine cardiomyocytes // Circ. Res. 2006. Vol. 99, № 11. Vol. 1216-1224. 4. Boyett M.R., Inada S., Yoo S., Li J., Liu J., Tellez J., Greener I.D., Honjo H., BilleterR., LeiM., Zhang H., EfimovI.R., Dobrzynski H. Connexins in the sinoatrial and atrioventricular nodes// Adv. Cardiol. 2006. Vol. 42. P. 175-197. 5. De Bakker J.M., van Rijen H.M. Continuous and discontinuous propagation in heart muscle // J. Cardiovasc. Electrophysiol. 2006. Vol. 17,№5. P.567-573. 6. Delorme B., Dahl E., Jarry-Guichard T., Briand J.P., Willecke K., Gros D., Theveniau-Ruissy M. Expression pattern of connexin gene products at the early developmental stages of the mouse cardiovascular system // Circ. Res. 1997. Vol. 81, №3. P.423-437. 7. FirouziM., RamannaH., KokB., JongsmaHJ., Koeleman B.P.C., Doevendans P.A., Groenewegen W.A., Hauer R.N.W. Association of human connexin40 gene polymorphisms with atrial vulnerability as a risk factor for idiopathic atrial fibrillation. // Circ. Res. 2004.Vol. 95, № 4. P. e29-e33. 8. Firouzi M., Ramanna H., Kok B., Jongsma H.J., Koeleman B.P.C., Doevendans P.A., Groenewegen W.A., Hauer R.N.W. Association of human connexin40 gene polymorphisms with atrial vulnerability as a risk factor for idiopathic atrial fibrillation // Circ. Res. 2004.Vol. 95, № 4.P. e29-e33. 9. GollobM.H., Jones D.L., KrahnA.D., Danis L., GongX.Q., Shao Q., Liu X., Veinot J.P., Tang A.S., Stewart A.F., Tesson F. , Klein G.J., Yee R„ Skanes A.C., Guiraudon G.M., Ebihara L., Bai D. Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation // New Eng. J. Med. 2006. Vol. 354, № 25. P. 2677-2688. 10. Groenewegen W.A., Firouzi M., Bezzina C.R., Vliex S., Langenl.M., Sandkuijl L., SmitsJ.P.P., HulsbeekM., RookM.B., Jongsma H.J., Wilde A.A.M. A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill//Circ. Res. 2003. Vol. 92, № 1. P. 14-22. 11. JuangJ.M., ChernY.R., TsaiC.T., ChiangF.T., LinJ.L., Hwang J.J., Hsu K.L., Tseng C.D., Tseng Y.Z., Lai L.P. The association of human connexin 40 genetic polymorphisms with atrial fibrillation // Int. J. Cardiol. 2007. Vol. 116, №1. P. 107-112. 12. Kanagaratnam P., Rothery S., Patel P., Severs N.J., Peters N.S. Relative expression of immunolocalized connexins 40 and 43 correlates with human atrial conduction properties //J. Am. Coll. Cardiol. 2002. Vol. 39, № 1. P. 116-123. 13. Mehta A.V., Chidambaram B., Garrett A. Familial symptomatic sinus bradycardia // Ped. Cardiol. 1995. Vol. 16, №5. P. 231-234. 14. Soemedi R., Topf A., Wilson I.J., Darlay R., Rahman T., Glen E., Hall D., Huang N., Bentham J., Bhattacharya S., Cosgrove C., Brook J.D., Granados-Riveron J., Setchfield K., Bu'Lock F., Thornborough C., Devriendt K., Breckpot J., Hofbeck M., Lathrop M., Rauch A., Blue G.M.,. Winlaw D.S, Hurles M., Santibanez-Koref M., Cordell H.J., Goodship J.A., Keavney B.D. Phenotype-specific effect of chromosome 1 q21.1 rearrangements and GJA5duplications in 2436 congenital heart disease patients and 6760 controls // Hum. Mol. Genet. 2012. Vol. 21, № 7. P. 1513-1520. 15. White T.W., Paul D.L. Genetic diseases and gene knockouts reveal diverse connexin functions // Annu. Rev. Physiol. 1999. Vol. 61. P. 283-310. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22763 Description Authors Annotation Keywords Reference List Comments Statistics Ranchaeva N. A., Yurchuk V. A. Hemodynamic features in children with extrahepatic portal hypertension in cavernous transformation of portal vein pre and postoperatively of porto-systemic shunting. Siberian medical review. 2014; № 5: 63-67. (In Rus.). Authors Ranchaeva N. A. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; teeda-ego@mail.ru Yurchuk V. A. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; teeda-ego@mail.ru Annotation The aim oT the research. To study the changes of organ hemodynamics after portosystemic shunting in children with extrahe- patic portal circulation unit on the background of cavernous transformation of the portal vein. Materials and methods. Were examined the changes in liver hemodynamics in 33 children aged 4 to 7 years old with extrahe- patic portal hypertension. Results. It was established that after the operation of portosystemic shunting was significantly reduced portal hemodynamics and values of the pulsation and resistive vascular resistance of the liver. Conclusion. After operation significantly unloaded the portal system, that is the prevention of gastrointestinal bleeding in extra- hepatic portal hypertension. Keywords: extrahepatic portal hypertension, hemodynamics, portosystemic shunting Reference List: 1. Zubarev A.V., Shipov O.Yu., Syutkin V.E., IvanikovI.O. Portal hypertension: diagnostic capabilities of ultrasound Doppler technigues // Echography - 2001. Vol. 2, №1,- P.6-13. 2. Vychuzhanin D.V., Chernousov A.D., Afukova O.G. Ultrasonography in the diagnosis of cirrhosis // Physician. 2011. №6. P. 82-85. 3. Kudryavtseva A.V., Kotiv B.N., Dzidzava I.I., Zhestovs- kaya S.I. Portal hypertension syndrome // Medical Imaging. 2010. №5. P.21-36. 4. Kuvaeva L.A. Bleeding from esophageal varices// Handbook of Feldsher and Midwife. 2011. №5. P.49-51. 5. Mishina T.P. Status of central hemodynamics in the surgical treatment of extrahepatic portal hypertension in children: Autoabstract Dis. Cand. Med. Sc. M., 2011. 48 p. 6. Razumovsky A.Yu., Rachkov V.E. Central hemodynamics in the surgical treatment of children with extrahepatic portal hypertension syndrome // Pediatric Surgery. 2009. № 2. P. 26-30. 7. Rachkov V.E., Razumovsky A.Yu., FeoktistovaE.V.Mezo- portal shunting at extrahepatic portal hypertension in children: 10 years of observations // Annals of Surgery. 2010. № 6. P. 46-50. 8. Bambini D.A., Superina R., Almond P.S., Whitington P.F., Alonso E. Experience with the Rex-shunt (mesenterico-left portal bypass) in children with extrahepatic portal hypertension //J. Pediatric Surgery. 2000. № 35(1). P. 13-18. 9. Bolondi L: Morphological and hemodynamic changes in the portal venous system after distal spleno-renal shunt: an ultrasound and pulsed doppler study // Hepatology. 1988. № 8. P. 652-657. 10. D'Amico G., Pagliaro L., Bosch J. The treatment of portal hypertension: a metaanalitic review//Hepatology. 1995. № 22 - P. 332-243. 11. Leen E., Goldberg J. A., Anderson W. J., Robertson J., Moule B., Cooke T.G., McArdle C.S. Hepatic perfusion changes inpatientswithlivermetastases: comparison with those patients with cirrhosis//Gut. 1993. Vol. 34. №4. P.554-557. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22767 Orlova G.M., Nebesnyh A.L. ETHNIC FEATURES OF METABOLIC SYNDROME IN THE BAIKAL REGION: FOCUS ON ARTERIAL HYPERTENSION Pages: 67-71 Description Authors Annotation Keywords Reference List Comments Statistics Orlova G. M., Nebesnyh A. L. Ethnic features of metabolic syndrome in the Baikal region: focus on arterial hypertension. Siberian medical review. 2014; № 5: 67-71. (In Rus.). Authors Orlova Galina Mikhailovna Dr.Med.Sc., Professor, the Head of the Department of Hospital Therapy; Irkutsk State Medical University, Ministry of Health of the Russian Federation; vicgal@yandex.ru Nebesnyh A. L. ; Irkutsk State Medical University, Ministry of Health of the Russian Federation; nastjabugaenk@rambler.ru Annotation The aim of the research. To establish the ethnic characteristics of arterial hypertension in patients with metabolic syndrome in the Baikal region. Materials and methods. The study included 145 patients, 71 - Buryat and 74 - Russian aged 36 to 79 years old. Results. Hypertension - equally frequent component of the metabolic syndrome in Russian and Buryat ethnic groups. The women of both ethnic groups have higher systolic blood pressure (SBP) compared with men, and women-Buryat - significantly higher SBP compared with Russian women. Conclusion. Identified ethnic features are important in planning the treatment of metabolic disorders in the Buryat ethnic group. Keywords: arterial hypertension, metabolic syndrome, Buryat and Russian population Reference List: 1. Abilova S.S. Intensity of atherosclerotic lesion of carotid arteries in patients with metabolic syndrome in combination and without coronary heart disease // Bulletin of the Kyrgyz-Russian Slavic University. 2009. Vol. 9, № 8. P. 122-125. 2. Malakshinova Z.H., Danzanova Ts.D., Madyeva L.D., Dolhonova T.V., Bubeev V.B., Shestov D.B. The prevalence of hypertension among the population of Ulan-Ude // Siberian Medical Journal (Irkutsk). 1997. Vol. 9, № 1-2. P. 34-36. 3. Mamedov M.N. Metabolic syndrome in Russia: prevalence, clinical features and treatment. M .: FGUP Publ. «Izvestia» Administration of the President of RF, 2011. 160p. 4. Ogarkov M.Yu., Barbarash O.L., Kazachek Ya.V., Kvit- kova L.V., Polikutina O.M., Barbarash L.S. The prevalence of metabolic syndrome X components in the indigenous and non-indigenous population of Mountain Shoria // Bulletin SB RAMS. 2004. № 1. P. 108-111. 5. Lekhanova E.N., Buganov А.А. Svaykina E.V. Features of mineral metabolism of the population of the Far North and hypertension in Yamal // Bulletin of Regenerative Medicine. 2009. № 6. P. 27-29. 6. Uvarova T.E., Burtceva T.E., Sofronova S.I., Efremova S.D., Gol'derova A.S. Blood lipid profile and features of lipid metabolism disorders in the Indigenous Peoples of Northern Yakutia // Far East Medical Journal. 2012. № 3. P. 85-88. 7. Shedoeva M.N. Features of the metabolic profile in patients with coronary heart disease and hypertension of different ethnicity // «Actual issues of Clinical and Experimental Medicine», Materials of the Scientific-Practical Conference of Young Scientists. St. Petersburg. 2003. P. 5. 8. Grundy S.M., Cleeman J.I., Daniels S.R., Donato K.A., Eckel R.H., Franklin B.A., Gordon D J., Krauss R.M., Savage P J., Smith S.C., Spertus J.A., Costa F. Diagnosis and management of the Metabolic syndrome // Circulation. 2005. Vol. 112. P. 2735-2752. 9. Tillin T., Forouhi N., Johnston D.G., McKeigue P.M., Chaturvedi N., Godsland I.F. Metabolic syndrome and coronary heart disease in South Asians, African Caribbeans and white Europeans: a UK population based cross-sectional study // Diabetologia. 2005. Vol. 48. P. 649-656. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22809 Description Authors Annotation Keywords Reference List Comments Statistics Bersenyeva 0. A., Ageeva E. S. Peculiarities of metabolic syndrome during menopause in women of Khakasia. Siberian medical review. 2014; № 5: 71-74. (In Rus.). Authors Bersenyeva O. A. ; Khakas State University of N.F. Katanov; ryngl@rambler.ru Ageeva E. S. ; Federal State Budgetary Institution of higher education «Khakassia State University named N. F. Katanov», Abakan; Ageevaeliz@iamblei.iu Annotation The aim of the research. Estimation of features at anamnestic, anthropometric and laboratory data of the metabolic syndrome among indigenous and immigrant women of the Republic of Khakasia in menopause. Materials and methods. Were examined 181 patients female with abdominal obesity, representatives of indigenous (Khakasian) and alien (Europeoids) population of Khakasia. All examined patients were in menopausal period. Were studied anthropometric and biochemical parameters. Results. Was identified prevalence of anthropometric indicators of the study (ОТ, OB) in Europeoids, compared with Khakasian women. It is shown that the change in fat metabolism (TG, TC, LDL cholesterol and HDL cholesterol) were more pronounced in female Europeoids, compared with Khakasian women. Conclusion. The study of characteristics of a menopausal metabolic syndrome is aimed to the development of effective preventive and therapeutic activity to reduce this pathology. Keywords: Metabolic syndrome, total cholesterol, lipoproteins, menopause, Khakasian Reference List: 1. Baranova E.I., Bol'shakova O.O. Metabolic cardiovascular syndrome in postmenopause // Reviews of Clinical Cardiology. 2005.№1. P.2-11. 2. Beskrovniy S. V., Gaivoronskikh D.I. Autumn of the woman: hormonal profile and clinical picture of menopause (lecture for medical practitioners) // Terra Medica Nova. 2010. №1. P. 38-43. 3. Grebennikova E.K., Tskhai V.B., MedvedevaN.N. Constitutional features of women with hyperplastic diseases of the uterus // Siberian Medical Review. 2012. № 4. P. 37-40. 4. Gladkaya V.S., Egorova A.T. The peculiarities of pregnancy and childbirth in women living in rural areas of the Republic of Khakasia //Siberian Medical Journal (Tomsk). 2008. № 1. P.60-63. 5. Efremenko Yu R., Koroleva E.F., Kontorshchikova K.N. Evaluation of the role of biochemical parameters in the diagnostic picture of the metabolic syndrome using discriminant analysis // Modern Technologies in Medicine. 2012. №4. P. 85-88. 6. Krivoshapkina Z.N., Mironova G.E., Olesova L.D., Yakovleva A.I., Sofronova S.I., Zakharova F.A. Frequency of dyslipidemia among population of Yakutia //Yakutsk Medical Journal. 2007. №3. P. 24-26. 7. Metabolic syndrome. M.: MED Press Inform, 2007. 224 p. 8. Pisareva L.F., Odintsova I.N., Ananina O.A., Stukanov S.L., Stolyarova V.A., Pavlenko O.A., Samoilova Yu.G., Oleinik O.A. Ethnic features of anthropometric indices of the hormonal status in women living in the Siberian region // Siberian Medical Journal (Tomsk). 2011. Vol. 26, № 4, Is. 2. P. 222-226. 9. Terekhovskaya I.G., El'chinova G.I., Kriventsova N.V., Khidiya- tova I.M., Husunutdinova E.K., Osipova E.V., Zinchenko RA. Age of menopause and reproduction parameters in rural Russians, Udmurts andBashkiisofRussia//HumanEcology. 2008. № 8. P. 12-16. 10. Shtygasheva O.V., Ageeva E.S., Kharkov V.N., Stepanov V.A. Genes and disease of Khakasians. Krasnoyarsk: Polikor, 2010 - 296 p. 11. AlbertiK. G., Eckel R. H., Grundy S. M., Zimmet P. Z., Cleeman J.I., Donato K. A., Fruchart J. C, James W. P., Loria С. M., Smith S. C. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity// Circulation. 2009. Vol. 20. P. 1640-1645. doi: 10.1161/CIRCULATIONAHA. 109.192644. Epub 2009 Oct 5. 12. Fiuza M., Cortez-Dias N., Martins S., Belo A. Metabolic syndrome in Portugal: prevalence and implications for cardiovascular risk - result from the VALSIM Study // Rev Port Cardiol. 2008. Vol. 27, № 12. P. 1495-1529. 13. Kelishadi R., Gharipour M., Sadri G.H., Tavasoli A.A., Amani A. Cardiovascular disease risk factors, metabolic syndrome and obesity in an Iranian population // Eastern Mediterranean Health Journal. 2008. Vol. 14, №5. P. 1070-1079. 14. Kue Young T., Chateau D., Zhang M. Factor analysis of ethnic in three Canadian populations // Am. J. Human. Biol. 2002. Vol. 14. P. 649-658. 15. Magi L., Stramenga C., Morosini P. Prevalence of the metabolic syndrome among Italian adults. Finding from the SIMAP study//Recenti Prog Med. 2005. Vol. 96, №6. P.280-283. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22812 Viktorova I.A., Lisnyak M.V., Trukhan D.I. INFLUENCE OF SOCIO-DEMOGRAPHIC AND PSYCHOLOGICAL FACTORS ON COMMITMENT TO ANTI HYPERTENSIVE THERAPY Pages: 75-78 Description Authors Annotation Keywords Reference List Comments Statistics Victorova I.A., Lisnyak M. V., Trukhan D.I. Influence of socio-demographic and psychological factors on commitment to antihypertensive therapy. Siberian medical review. 2014; № 5: 75-78. (In Rus.). Authors Viktorova I. A. ; Omsk State Medical Academy; vic-iima@mail.ru Lisnyak M. V. ; Omsk State Medical Academy; lisnyak80@mail.ru Trukhan D. I. ; Omsk State Medical Academy; trukhan@mail.ru Annotation The aim of the research. Estimation of the influence of socio-demographic and psychological factors on commitment to treatment of patients with arterial hypertension (AH) and anxiety disorders (TP). Materials and methods. The study involved 209 patients with hypertension and anxiety. Adherence to treatment was assessed by a test of the Morisci-Green. Results. Were identified the following risk factors of low adherence to treatment of hypertension: the lack of family, refuse to take drugs in the history, high level of stress at work place and TP. Conclusion. It is important to create a “portrait" of the patient, identifying its existing socio-demographic and psychological factors that reduce adherence to therapy. Keywords: hypertension, family, stress, anxiety, commitment Reference List: 1. Andryushchenko A.V., Drobizhev M.Yu., Dobrovolsky A.V. Comparative evaluation scales CES-D, BDI, and HADS in the diagnosis of depression in general practice // Journal of Neurology and Psychiatry named after S.S. Korsakov. 2003. №5. P. 80-86. 2. Petri A., Sebin K. Illustrative statistics in medicine: Transl. from English. M.: GEOTAR-MED, 2003. 144 p. 3. Trukhan D.I., Tarasova L.V. Optimization of drug therapy for coronary heart disease and hypertension: the choice of ACE inhibitor// Systemic Hypertension. 2014. № 1. P. 73-77. 4. Trukhan D.I., Pavlova T.V., Tarasova L.V., Viktorova I. A. Optimization of drug treatment of hypertension in the framework of research, educational and improving program PERSPECTIVE // Handbook of Policlinik Physician. 2014. №1.-P.16-20. 5. Kharkov E.I., Davydov E.L. Features of the guality of life and psychological characteristics of elderly patients with diseases of the cardiovascular system and the way of their correction // Russian Journal of Cardiology. 2010. №3. P.53-57. 6. KharkovE.I., Davydov E.L., Shulmin A.V. Elderly patient and hypertension: the peculiarities and treatment (post I) // Siberian Medical Review. 2010. № 3. P. 3-8. 7. Shal'nova S.A., Balanova Yu.A., Konstantinov V.V. Hypertension: prevalence, awareness, antihypertensive medications, and the effectiveness of treatment in the population of the Russian Federation // Russian Journal of Cardiology. 2006. № 4. P. 45-50. 8. Shal'nova S., Kukushkin S., Manoshkina E., Timofeeva T. Hypertension and adherence to therapy // Physician. 2009. № 12. P. 39-42. 9. Brunenberg DE, Wetzels GE, Nelemans PJ, Dirksen CD, SeverensJL, Staffers HE, SchoutenJS, PrinsMH, deLeeuwPW, Joore MA. Cost effectiveness of an adherence-improving programme in hypertensive patients // Pharmacoeco- nomics.2007. №25(3). P. 239-251. 10. Coleman Cl, limone B, Sobieraj DM, Lee S, Roberts MS, Kaur R, Alam T. Dosing freguency and medication adherence in chronic disease // J. Manag. Care Pharm. 2012. №18(7). P.527-539. 11. Irvin MR, Shimbo D, Mann DM, Reynolds K, Krousel-Wood M, Limdi NA, Lackland DT, Calhoun DA, Oparil S, Muntner P. Prevalence and correlates of lowmedication adherence in apparent treatment-resistant hypertension//J. Clin. Hypertens (Greenwich). 2012. № 14(10). P. 694-700. 12. Mancia G., Fagard R., Narkieewicz R.,Redon J., Zanchetti A., Bahm M. et al. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC). 2013 ESH/ESC Guidelines for the management of arterial hypertension//J. Hypertens. 2013. № 31. P. 1281-1357. 13. Morisky D.E., Ang A., Krousel-Wood M. and Ward H.J. Predictive Validity of a Medication Adherence Measure in an Outpatient Setting // The Journal of Clinical Hypertension. 2008.№ 10.P.348-354. 14. World Health Organization: Adherence to long-term therapies, evidence foraction.URL:http://whglibdoc.who.int/ publications/2003/9241545992.pdf/. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22824 Popova T.E., Shnayder N.A., Petrova M.M., Kantimirova E.A., Gazenkampf K.A., Ermakov S.K., Nikolaeva T.Y. COMPUTER PALLESTEZIOMETRY AS A PROSPECTIVE METHOD OF DIAGNOSTICS SENSORY FORM OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY Pages: 79-85 Description Authors Annotation Keywords Reference List Comments Statistics Popova T. E., Shnayder N. A., Petrova M. M., Kantimirova E. A., Gazenkampf K. A., Diuzhakov S. K., Nikolaeva T. Y. Computer pallesteziometry as a prospective
method of diagnostics sensory FORM of chronic inflammatory demyelinating polyneuropathy. Siberian medical review. 2014; № 5: 79-85. (In Rus.). Authors Popova Tatyana Egorovna Cand.Med.Sc., Associate Professor, the Department of Medical Genetics and Clinical Neurophysiology of Institute of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; tata2504@yandex.ru Shnayder Natalya Alekseevna MD, PhD, Prof., Head of the Department of Medical Genetics and Clinical Neurophysiology of Institute of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; 660022, г. Красноярск, ул. Партизана Железняка, д. 1; тел.: 8(391) 2212449; e-mail: nataliashnayder@gmail.com Petrova Marina Mikhailovna MD, PhD, Prof., Head of the Department of Outpatient Therapy, Family Medicine and HL with a course of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; 660022, Красноярск, ул. Партизана Железняка, 1;тел.:8 (391)2200628; e-mail: stk99@yandex.ru Kantimirova Elena Anatolyevna Candidate of Medical Sciences, Associate Professor of the Department of Medical Genetics and Clinical Neurophysiology Institute for Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; kantilea@mail.ru Gazenkampf K. A. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; nerusss@mail.ru Ermakov S. K. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; caEgono@yandex.ru Nikolaeva Tatyana Yakovlevna MD, PhD, Head of Department of Neurology and Рsychiatry; North-East Federal University named after M.K. Ammosov; tyanic@mail.ru Annotation The aim oT the research. Evaluation of computer pallesteziometry as a prospective method for the diagnosing of demyelinating lesions of thick filbers in sensory form ofCIDP. Materials and methods. The study involved 77 people with sensory variant of CIDP based at the University Hospital of KrasSMU named after prof. V.F. Voyno-Yasenetsky. The age of patients ranged from 13 to 61 years old, the median age was 30 years. Methods of diagnosis: clinical neurological, neurophysiological. Results. Modified technique of computer pallesteziometry using domestic diagnostic equipment “Vibrotesters MBN" VT-02-1 is a sensitive method for diagnosing of sensory form ofCIDP, including the early stages of the disease and can be recommended for widespread use in clinical practice. Conclusion. In the differential diagnosis of the severity of sensory disorders at CIDP the most relevant is the study of the state of vibration sensitivity by the method of computer pallesteziometry. Keywords: chronic inflammatory demyelinating polyneuropathy (CIDP), diagnosis, neurophysiology, computer pallesteziometry Reference List: 1. Diagnosing of diabetic neuropathy// Ed. N.A. Schneider, M.M. Petrova. M.: Publishing House Medica, 2014.288 p. 2. Popova T.E., Schneider N. A., PetrovaM.M., Goncharova S.I., Gazenkampf K.A., Nikolaeva T.Ya. Dynamics of vibration sensitivity changes according to computer pallesteziometry in acquired and genetically determined forms of polyneuropathy, class mielinopaty // Siberian Medical Review. 2014. №4. P. 69-74. 3. Schneider N.A., Kantimirova E.A. Paraneoplastic polyneuropathy: definition, etiopathogenesis, diagnosis //Siberian Medical Review. 2010. №61. P. 12-16. 4. Bromberg M.B. Review of the evolution of electrodiagnostic criteria for chronic nflammatory demyelinating polyradiculoneuropathy//Muscle Nerve. 2011. Vol. 43, № 6. P. 780-794. 5. DalakasM.C.Clinicaltria]sinCIDPandchronicautoimmune inflammatory demielinating polyradiculoneuropathy //J. PeripherNerv. Syst. 2012. Vol. 17. P. 34-39. 6. Dalakas M.C. Medscape. Advances in the diagnosis, pathogenesis and treatment of CIDP // Nat. Rev. Neurol. 2011. Vol.7,№9. P.507-517. 7. Harbo T., Andersen H., Jakobsen J. Length-dependent weakness and electrophysiological signs of secondary axonal loss in chronic inflammatory demyelinating polyradiculoneuropathy // Muscle Nerve. 2008. Vol. 38, № 2. P. 1036-1045. 8. Hartung H.P., Lehmann H.C., Willson H.G. Peripheral neuropaties: establishing common clinical research standarts for CIDP // Nat. Rev. Neurol. 2011. Vol. 16. P. 63-67. 9. Iijima M., Koike H., Hattori N., Tamakoshi A., Katsuno M., Tanaka F., Yamamoto M., Arimura K., Sobue G. Prevalence and incidence rates of chronic inflammatory demyelinating polyneuropathy in the Japanese population //J. Neurol. Neurosurg. Psychiatry. 2008. Vol. 79, № 9. P. 1040-1043. 10. Koski C.L., Baumgarten M., Magder L.S., Barohn R.J., Goldstein J., Graves M., GorsonK.,HahnA.F., Hughes R.A., Katz J., Lewis R.A., ParryGJ., vanDoom P., Comblath D.R. Derivation and validation of diagnostic criteria for chronic inflammatory demyelinating polyneuropathy // J. Neurol. Sci. 2009. Vol. 277. P. 1-8. 11. Peltier A.C., Donofrio P.D. Chronic inflammatory demyelinating polyradiculoneuropathy: from bench to bedside //Semin. Neurol. 2012. Vol. 32, №3. P. 187-195. 12. Rajabally Y.A., Chavada G. Lewis-Sumner syndrome of pure upper-limb onset: diagnostic, prognostic, and therapeutic features//Muscle Nerve. 2009. Vol. 39, №2. P.206-220. 13. Rajabally Y.A., Nicolas G., Pmret F., Bouche P., Van den Bergh P.Y. Validity of diagnostic criteria for chronic inflammatory demyelinating polyneuropathy: a multicentre European study//J. Neuro.l Neurosurg. Psychiatry. 2009. Vol. 80, №12. P. 1364-1368. 14. Schneider-Hohendorf T., Schwab N., Шеу1ег N., Gpbel K., Sommer C., Wiendl H. CD8+ T-cell immunity in chronic inflammatory demyelinating polyradiculoneuropathy //Neurology. 2012. Vol. 78. P.402-408. 15. Stabgen J.-P. Biological agents for chronic inflammatory demielinating polyradiculoneuropathy // European Neurological Review. 2013. Vol. 8, № 1. P. 57-61. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22778 Description Authors Annotation Keywords Reference List Comments Statistics Filimonova E. S., Tarasenko S. L., Dykhne Y. A., Khlebnikova F. B. Evaluation of effectiveness cytological method for the diagnosis of pretumor and tumor cervical
disease. Siberian medical review. 2014; № 5: 86-88. (In Rus.). Authors Filimonova E. S. ; A branch of the Siberian Clinical Center FMBA Russia Clinical Hospital № 42, Zelenogorsk, Krasnoyarsk Territory; filimonova_es@skc-fmba.ru Tarasenko S. L. ; A branch of the Siberian Clinical Center FMBA Russia Clinical Hospital № 42, Zelenogorsk, Krasnoyarsk Territory; swetarasenko@yandex.ru Dykhno Yu. A. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; dykhno_yury@mail.ru Khlebnicova F. B. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; faina@mail.ru Annotation The aim of the research. To assess the diagnostic efficacy of the cytologic method in the diagnosis of precancerous and cancer of the cervix. Materials and methods. Were analyzed the results of cytological examination of the cervix, derived from the 71 patients. The effectiveness of cytology was evaluated by comparing the obtained results of cytologic findings with routine histology. Obtained material for cytological examination was fixed for 3 minutes by eosin methylene blue at May-Grunwald and stained with azuxe- eosin mixture at Romanovsky. Results. During cytology were obtained high rates of results (83.1 %) and reliability (84.6 %), which demonstrate sufficient efficacy of the cytologic method. Conclusion. The results indicate that cytological method is highly effective in the diagnosis of precancerous (dysplastic) and cancer processes of the cervix. Keywords: cervical cancer, dysplasia, cytological examination Reference List: 1. Malignancies in Russia in 2011 (morbidity and mortality) / Ed. V.I. Chissova, V.V. Starinskiy, G.V. Petrova. M .: FGBU MNIOI named after P.A. Hertsen of Ministry of Health, Russia, 2013 - 289 p. 2. Laboratory diagnosis / Ed. V.V. Dolgov, O.P. Shevchenko. M.: Reafarm, 2005 - 440 p. 3. Karpova Yu. V., Vershinina M.G., Kudryavtseva L.V. Cervical cancer: the current state of the problem // Laboratory Service. 2012. № 1 (1). P. 24-34. 4. Kostyuchek I.N., Vorobyov S.L. Approaches to cervical cancer screening // Handbook of the Head of CDL. 2012.№ 7,- P. 3-9. 5. Jemal A., BrayF., Center M.M., FerlayJ., Ward E., Forman D. Global cancer statistics // CA Cancer J Clin. 2011. Vol.61,№2. P.69-90. 6. Schiffman M., Wentzensen N. From Human Papillomavirus to Cervical Cancer // The American College of Obstetricians and Gynecologists. 2010. Vol. 116,№ 1. P. 177-185. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22741 Nekrasova K.S. STATE OF COGNITIVE SPHERE IN CHILDREN AFTER PURULENT AND SEROUS MENINGITIS Pages: 89-91 Description Authors Annotation Keywords Reference List Comments Statistics Nekrasova K. S. State of cognitive sphere in children after purulent and serous meningitis. Siberian medical review. 2014; № 5: 89-91. (In Rus.). Authors Nekrasova K. S. ; Tyumen state medical academy; ksnekrasova@gmail.com Annotation The aim of the research. Assessment of the severity of cognitive disorders in school-age children, have had purulent and serous meningitis. Materials and methods. The study involved 90 children aged 6 to 17 years old in the period of residual effects (after 3 years). The control group consisted of 30 children of the same age and sex. Results. Were identified backlog over all functions of attention. Conclusion. Identified cognitive disorders require obligatory dispensary observation with active neurorehabilitation therapy. Keywords: meningitis, children, cognitive function Reference List: 1. Ivanova M.V., Vil'nits А.А., Scripchenco N.V. Contemporary approaches to the rehabilitation of patients with bacterial meningitis // Epidemiology and Infectious Diseases. 2005. №3. P.61-64. 2. Kozhushko N.Yu. Diagnosis and correction of study lowering in children. Childhood. Press.: St. Petersburg, 2008. P. 121. 3. PivnevaO.V., ZakharychevaT.A., KostitsinK.N. Premor- bid state in preschool children - reconvalescents by enterovirus meningitis // Far East Medical Journal. 2010. № 4. P.24-25. 4. Scripchenko N.V., Egorova E.S. Using of cytoflavin in complex therapy of neuroinfections in children // Journal of Neurology and Psychiatry. 2011. Vol. 111, № 9. P.28-31. 5. Fomin V.V., Sabitov A.U. Clinical and immunological features of enterovirus meningitis in children // Bulletin of Ural Medical Academy of Science. 2008. №2. P.144-146. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22777 Tikhonova E.P., Kuz'mina T.Y., Sergeevа I.V., Tikhonova Y.S., Derevyannykh E.V. THE CASE OF INFECTIOUS MYOCARDITIS AT TRICHINOSIS Pages: 91-94 Description Authors Annotation Keywords Reference List Comments Statistics Tihonova E. P., Kuzmina T. U., Sergeeva I. V., Tihonova U. S., Derevyannykh E. V. The case of infectious myocarditis at trichinosis. Siberian medical review. 2014; № 5: 91-94. (In Rus.). Authors Tikhonova Elena Petrovna Dr. Med. Sc., Professor, Head of the Department of Infectious Diseases and Epidemiology with the course of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; tihonovaep@mail.ru Kuz'mina Tatyana Yuryevna Cand. Med. Sc., Associate Professor, the Department of Infectious Diseases and Epidemiology with the Course of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; tkuzmina_24@mail.ru Sergeevа Irina Vladimirovna Cand.Med.Sc., Associate Professor, the Department of Infectious Diseases and Epidemiology with the course of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; infeccia7979@mail.ru Tikhonova Yulia Sergeevna Assistant of the Department of Infectious Diseases and Epidemiology with the course of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; tihonovaus@mail.ru Derevyannykh E. V. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; rusene@mail.ru Annotation This article presents a clinical case of late diagnosis of trichinosis, complicated by infectious-allergic myocarditis in a patient with obesity of the third grade. The above example proves necessity for increased vigilance in interpreting the clinical symptoms of the disease based on epidemiological history. Keywords: trichinosis, severe course, myocarditis Reference List: 1. Bronshtein А.М., Malyshev N. A. Human helminthiasis: a brief guide for physicians. M.: Publishing House «Rusprint» 2010.-112 p. 2. Bronshtein A.M., Sergiev V.P., PoletaevaO.G. Trichinosis: a manual for physicians. M., 2003. 34 p. 3. Tokmalayev A.K., Kozhevnikov G.M. Clinical Parasitology: protozoozyand helminthiases. M.: «Medical Information Agency, Ltd», 2010. 432 p. 4. Tikhonova E.P., Anisimova E.N., Kuz'mina T.Yu., Minoranskaya E.I. Helminthiasis: a manual for physicians, interns and residents. Krasnoyarsk, 2009 - 101 p. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22758 Popova O.M., Sokolovskaya M.V., Buyankina R.G. SIMULATION OF INTEGRATED MANAGEMENT SYSTEM OF EDUCATIONAL ORGANIZATION BASED ON THE PRINCIPLES OF SUSTAINABLE DEVELOPMENT Pages: 94-99 Description Authors Annotation Keywords Reference List Comments Statistics Popova О. M., Sokolovskaya M. V., BuyankinaR. G. Simulation of integrated management system of educational organization based on the principles of sustainable
development. Siberian medical review. 2014; № 5: 94-99. (In Rus.). Authors Popova Oksana Mikhaeloma Employment manager of Institute of Postdegree Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; diman_abatak@mail.ru Sokolovskaya Marina Vladimirovna the Teacher of the highest gualification category, the Specialist in QMS of Quality Management Department; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; sokolovskaya-marina@yandex.ru Buyankina Rimma Gennadievna Cand.Med.Sc, Associate Professor of Department of Dentistry Clinics, Institute of Post-diploma Education and Advanced Training, the Head of Quality Management Department; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; buyankinar@mail.ru Annotation The aim of the research. Development of the model for sustainable development of quality system in educational organization. Materials and methods. Were used the standards GOST ISO 9001-2011, GOST R ISO 9004-2010 and GOSTR 54598.1-2011. During the work were used the following methods: the method of expert assessment, comparative analysis, modeling. Results. Were identified areas of similarity and difference GOST ISO 9001-2011, GOST R ISO 9004-2010 and GOST R 54598.1- 2011; proposed a graphic model of the sustainable development of the quality system for educational organization. Conclusion. The developed model of sustainable development of the quality system for the educational organization will be the basis for creating integrated management system based on the principles of sustainable development, and the key to success in achieving its sustainable development. Keywords: integrated management system, quality management system, educational organization, standards ISO 9000, GOSTR 54598.1-2011, sustainable development Reference List: 1. Quality management as a basis for the creation of IP university management // Quality. Innovation. Education: Materials of the Second Scientific Conference. M.: Fond «Kachestvo», 2001. P. 3-5. 2. GOST ISO 9001-2011. Quality Management System. Requirements. Intr. 2013-01-01. M.: «Standartinform», 2012. 28 p. 3. GOST R 54598.1-2011 Organization Management. Guide for the Sustainable Development. Intr. 2011.12.07. M.: «Standartinform», 2012. 12 p. 4. GOST R ISO 9004-2010. Managing for the sustained success of organization. Approach based on the quality management - Intr. 2010-11-23. M.: «Standartinform», 2011. 41 p. 5. Guseva T.V. Integration as a natural stage in the development of management systems // Management in Russia and abroad. 2003. №5. P. 7-10. 6. Pazyuk Yu.V. Integrated Management Systems of Organization // Partners and competitors. 2004. № 11. P. 8-11. 7. Svitkin M.Z. Integrated Management Systems // Standards and Quality. 2004. № 2. P. 56-61. 8. Sitnichenko V.M., Stoyakin E.A. Integrated Management System - the basis of sustainable development of the enterprise //Methods of Quality Management. 2004. №8. P.4-8. 9. Troshin V.N. Integrated Management Systems - what is it? //Standards and Quality. 2002. № 11. P. 10-13. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22712 Description Authors Annotation Keywords Reference List Comments Statistics Zulin Ya. V., Kalinichenko A. V., Bortsov V. A., Kulikovskaya I. V., Romanenko M. Yu. Economic efficiency of policlinic branches system in solving the problem of territorial availability. Siberian medical review. 2014; № 5: 99-102. (In Rus.). Authors Zulin Ya. V. Cand.Med.Sc; Novosibirsk city polyclinic № 26; yvzouhne@onhne.nsk.su Kalinichenko A. V. D.Med.Sc., Professor; Novosibirsk State Medical University; Novosibirsk city consultative-diagnostic polyclinic № 27; kav007@ngs.ru Bortsov V. A. D.Med.Sc.; Novosibirsk State Medical University; Novosibirsk city consultative-diagnostic polyclinic № 27; va_bortsov@mail.ru Kulikovskaya I. V. ; Novosibirsk State Medical University; Novosibirsk city consultative-diagnostic polyclinic № 27; gomi2009@yandex.ru Romanenko M. Yu. ; Novosibirsk State Medical University; Novosibirsk city consultative-diagnostic polyclinic № 27; maguseva@yandex.ru Annotation The aim of the research. Assessment of the economic efficiency of the system of ambulatory medical organization branches in solving the problem of territorial availability. Materials and methods. Estimating the number of visits to clinics and emergency calls, evaluation of a day hospital clinic activity. Results. Economic efficiency is achieved through the effective use of day hospital and reduce the number of emergency calls. Conclusion. The developed model of the system of clinic branches makes optimum use of financial flows inhealth care. Keywords: territorial availability, the policlinic branches system, economic efficiency Reference List: 1. Vyalkov A.I. Actual problems of promoting public health and preventive activities control in the health care system // Problems of Health Management. 2009. №5. P. 5-16. 2. Guseva S.L. Organizational structure as a basis for the strategic management of the health care institution. // Health Economics. 2011. № 157. P. 5-8. 3. Svetlichnaya T.G., Tsyganova O. A., Kudryavtsev A.V.Assessment of satisfaction with medical care of patients of outpatient clinics (according to thesociological survey) / Health of the Russian Federation. 2010. №3. P. 18-21. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22704 Kovaleva G.K., Toropova G., Shelomentseva О.V., Zukov R.A. TECHNOLOGY OF THE POSITION TRAINING DURING THE TUITION IN THE MEDICAL HIGH SCHOOL Pages: 102-105 Description Authors Annotation Keywords Reference List Comments Statistics Kovaleva G. K., Toropova G. V., Shelomentseva О. V., Avdeeva E. A. Technology of the position training during the tuition in the medical high school. Siberian medical review. 2014; № 5: 102-105. (In Rus.). Authors Kovaleva G. K. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; gulmimkoYaleYa@mail.ru Toropova G.V. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; toropova.kgmu@yandex.ru Shelomentseva О. V. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; ov_shelom@mail.ru Zukov R. A. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; zukov_rus@mail.ru Annotation The aim of the research. To reveal the attitude of medical students to the use of technologies of developing training while learning the basic subjects (on example of the subject “Histology, Embryology and Cytology - Histology of the Mouth Cavity"). Materials and methods. Based on the methodology of developing positional training was prepared and tested a practical session on the subject “Histology, Embryology and Cytology - Histology of the Mouth Cavity" on theme "Endocrine System". On its results was carried out questionnaires of students of the second year on the specialty "Dentistry", 85 units of observation. Descriptive statistics of the results is presented by percentages and its standard errors. Results. It is shown that the modem student is ready, and with interest takes part in the various organizational methods of the educational process. At the same time, in the process of collective use of classical and developing methods, effectively assimilating and working through the educational information that is definitely aimed to the development of both professional and general cultural competence of students. Conclusion. Existing work has practical application to optimize the learning process in medical high school. Keywords: FGOS VPO, technology of positional training, survey results Reference List: 1. Azarova R.N., Zolotareva N.M. Development of competence passport: Methodical recommendations for organizers of design work and teaching staff of universities. M.: Research Center of the Quality Problems of Training Specialists, the Coordinating Council of Teaching Associations and Scientific-Methodological Councils of Higher School, 2010. 52 p. 2. Belyaeva M. A. Problems of education guality in the context of high school reform // Standards and Quality. 2002. №4. P.20-21. 3. Veraksa N.E. Model of positional students learning //Questions of Psychology. 1994. №3. P.122-129. 4. Veraksa N., I. Shiyan I., Shiyan 0. Methods of positional training of students / Visnik institutu rozvitku ditini. 2010. № 12. P. 109-115. 5. Elizova E.A. Communicative and semantic strategy of humanitarian education. Journal of Chita State University. 2010. №5(62). P. 70-75. 6. Rasskazov L.D. Upbringing work of the university curator in the context of globalization: the socio-philosophical analysis of the crisis in the educational system // Siberian Medical Review. 2014. №1. P.97-101. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22673 Description Authors Annotation Keywords Reference List Comments Statistics Petrova M. M., Kaskaeva D. S., Pilugina M. S., Pronina E. A., Danilova L. K. Social control of education quality in the medical high school. Siberian medical review. 2014; № 5: 106-110. (In Rus.). Authors Petrova Marina Mikhailovna MD, PhD, Prof., Head of the Department of Outpatient Therapy, Family Medicine and HL with a course of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; 660022, Красноярск, ул. Партизана Железняка, 1;тел.:8 (391)2200628; e-mail: stk99@yandex.ru Kaskaeva Darya Sergeevna Cand. Med. Sc., Associate Professor of the Department of Polyclinic Therapy, Family Medicine and Healthy Lifestyle with Postgraduate Courses; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; dashakas.ru@mail.ru Pronina E. A. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; ru@mail.ru Pronina Elena Alexandrovna Cand. Med. Sc, Assistant of the Department of Polyclinic Therapy, Family Medicine and Healthy Lifestyle with Postgraduate Courses; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; dnnny@mail.ru Danilina Elena Petrovna Cand.Med.Sc., Assistant Professor of Surgical Clinics and Diseases named after Prof. Y.M. Lubensky; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; LenaO-1961@mail.ru Annotation The aim of the research. To improve the educational process on subject "Healthy Lifestyle" was conducted anonymous questionnaires of students about satisfaction with the educational process in the Workbook. Materials and methods. In the survey took part 241 medical students, they responded to seven questions of the anonymous questionnaire. Results. Our analysis of the survey results allowed to reveal the strengths and weaknesses of the Workbook. Conclusion. Careful study of the identified deficiencies in the development of the next Workbooks will improve the quality of teaching in the medical high school. Keywords: social control, quality of education, pedagogy in medical school, Workbook Reference List: 1. Vvedenskiy V.N. Social control of the teacher of high school //Higher Education in Russia. 2014. №4. P. 120-127. 2. Gromkova M.T. Pedagogy of higher school: a tutorial. M.: Unity-dana, 2012. 446 p. 3. Danilova M.A., Serova I.A., Yagodina A.Yu. Workbooks - effective means of training in medical high school // Siberian Medical Review. 2013. №6. P. 100-103. 4. Karas' S.I., KetovP.N., Batalova O.V. Competence approach FGOS in medical high school // Bulletin of Baltic Federal University named after I. Kant. 2013. №5. P. 100-106. 5. Kaskaeva D.S., Pilyugina M.S., Manukhina E.A., Kostina V.V. Workbook on subject «Healthy Lifestyle» for auditorial and extracurricular work of students in speciality 060103 - Pediatrics /UnderEd.M.M.Petrova. Krasnoyarsk: Verso,Ltd, 2013. 216p. 6. Merkulova O.P. Problems of estimation of the educational process by students // Higher Education in Russia. 2012. №2.-P.18-24. 7. Petrova M.M., Kaskaeva D.S., Pilyugina M.S., Manukhina E.A., Kostina V.V., EvsyukovAA, Danilova L.K. The introduction of the Workbook on subject «Healthy Lifestyle» in the pedagogical process of medical high school // Modern Aspects of the Implementation of FGOS and FGT. The University Pedagogy. Krasnoyarsk: KrasSMU, 2013. P. 239-241. 8. Petrov M.M., Pronina E.A., Kaskaeva D.S., Pilyugina M.S., Danilova L.K., EvsyukovAA., Manukhina E.A. Experience of using the Workbook on subject «Healthy Lifestyle» in pedagogical process of medical high school // Effective management and organization of the educational process in the modern medical high school. The University Pedagogy. Krasnoyarsk: KrasSMU, 2014. P. 193-197. 9. Federal state educational standard of higher professional education in the specialty 060101.65 - Medicine. M., 2010 - 35 p. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22717 RESOLUTION OF THE INTERNATIONAL CONGRESS ON NEUROSCIENCE, Krasnoyarsk, 19-21 June, 2014 Pages: 110-111 Description Authors Annotation Keywords Reference List Comments Statistics Resolution of the International Congress on Neuroscience, Krasnoyarsk, 19-21 June, 2014. Siberian medical review. 2014; № 5: 110-111. (In Rus.). Authors Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22657 Description Authors Annotation Keywords Reference List Comments Statistics Kochetova L. V. Review of dissertation topics that were submitted in 2013 by the committee of dissertation defense D 208.037.02 in specialty 14.01.17 -
surgery. Siberian medical review. 2014; № 5: 112-115. (In Rus.). Authors Kochetova Lyudmila Victorovna Cand.Med.Sc., Associate Professor of the chair of general surgery, Academic Secretary of the Dissertation Council D 208.037.05; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; dissovetkrasgmu@bk.ru Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22636 Description Authors Annotation Keywords Reference List Comments Statistics То the 75тн anniversary of professor F.F. Tetenev. Siberian medical review. 2014; № 5: 116. (In Rus.). Authors Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 22620 |
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