ARCHIVE2024202320222021202020192018201720162015201420132012201120102009 |
Сибирское медицинское обозрение. 2015. № 4 View full text Количество просмотров : 8441Porovsky Ya. V., Tetenev F. F. Comorbidity in medical practice. Siberian Medical Review. 2015; 4:5-10. (In Rus.). DOI 10.20333/25000136-2015-4-5-10 Authors Porovsky Yaroslav Vitalievich M.D., Famulus of the department of propaedeutics of internal diseases; Siberian State Medical University; porovs@sibmail.com Tetenev Fedor Fedorovich ; ; ftetenev@list.ru Annotation This article discusses the questions of combined pathology. It was done the analysis of the literature, the historical aspect of the problem, results of the study the mechanisms for its development, features of the present-day medical patient. The study of the relationship between the most common diseases is important from a fundamental and applied point of view, since the knowledge of the specific formation mechanisms of comorbidity, the impact on the common pathogenetic link avoids polypragmasy. Keywords: comorbidity, terminology, mechanisms of development, treatment Reference List: 1. Belyalov F.I. Twelve theses of comorbidity // Clinical Medicine. 2009. Vol. 87, № 12. P. 69-71. 2. Belousov S.S., Novikov I.I. Role of molecular and immunological disorders in the pathogenesis of myocardial infarction and its modulation in the clinical practice // Medical Almanac. 2010. № 2. P. 66-69. 3. BarkhinaT.G., Ali-RizaA.E., SamsonovaM.V., Chernyaev A.L., Melnikov G,Ya., Vinokurov D.P. Pathomorphological features of microvascular wall of the bronchi in the workers of mining and chemical enterprise // Bulletin of Experimental Biology and Medicine. 2001. Vol. 132, № 10. P. 459-463. 4. Bychkovskaya LB., Stepanov R.P., Kirik O.V. Some new aspects of the radiosensitivity of slightly renewing tissues // Medical Radiology and Radiation Safety. 2003. Vol. 48, №6. P. 5-17. 5. Vertkin A.L., Rumyantsev M.A., Skotnikov A.S. Comorbidity in clinical practice. Part 1 // Arhiv of Internal Medicine.- 2011. № 1. P. 9-13. 6. Gazizova R.G., Ibragimova I.I., Askarova AN. Associations of genes polymorphisms predisposition to hypertensive disease among the Russians and Tatars at the Republic of Tatarstan // Scientific Notes of the Kazan State University. 2005. Vol. 147, № 3. P. 56-69. 7. GusevE.Yu., ChereshnevV.A. Evolution of inflammation //Cytokines and Inflammation. 2012. №4. P. 9-21. 8. Dvoretskiy L.I. Anemia in patients with chronic obstructive pulmonary disease: comorbidity or systemic manifestation? // Pulmonology. 2012. № 2. P. 5-11. 9. Ilicheva V.N. Comparative characteristics of the effect of low doses of ionizing radiation on the permeability of the microvasculature of various areas of the cerebral cortex // Bulletin of New Medical Technologies. 2011. Vol. XXVIII, №2.-P. 251-253. 10. Kabdrakhmanov K. Human conseguences of nuclear tests in Kazakhstan // Almaty: Glke. 2003. 336 p. 11. Cornetov N.A. Comorbidity of somatic illnesses and depressive disorders - a common problem in modern medicine // Scientific Notes of the St. Petersburg State Medical University. Named after Acad. LP. Pavlov. 2011. Vol. 18, № 4. P. 38-40. 12. Krylov A. A. To the problem of compatibility of diseases //Clinical Medicine. 2000. № 1. P. 56-59. 13. Kulikov E.S., Ogorodova L.M., Freidin M.B., Saltykova I.V., Deev LA., Selivanova P.A. The genetic patterns of severe treatment-resistant asthma according to transcriptome research: Analysis of gene ontology and KEGG pathways // Bulletin of Baltic Federal University named after I. Kant. Series: Natural Sciences. 2014. Vol. 1. P. 121-131. 14. Lyutykh V.P., Dolgikh A.P. Clinical aspects of low doses effect of ionizing radiation on human beings (general somatic disease) // Medical Radiology and Radiation Safety. 1998. Vol. 42, №2. P. 28-34. 15. Malygina N.A., Melentev A.S., Kostomarova I.V. Communication Hind III DNA polymorphism of lipoprotein lipase gene with a life expectancy of patients with coronary heart disease in elderly and senile age // Molecular Biology. 2001 - Vol. 35, № 5. P. 787-791. 16. Mitrofanov I.M., Nikolaev Yu.A., Dolgova N.A., Po-spelova T.I. Regional ieatures in present-day clinic oi internal diseases // Clinical Medicine. 2013. Vol. 91, № 36. P. 26-29. 17. Nikiiorov A.M. Health Effects oi the Chernobyl accident //Bulletin oiSPt.SMA named after I.I. Mechnikov. 2005. №1. P. 229-233. 18. Nurgazizova A.K. The origin, development and contemporary interpretation oi the concepts oi «Comorbidity» and «Polymorbidity»// Kazan Journal oi Medicine. 2014. Vol. 95, №2. P. 292-296. 19. Porovskiy Ya.V., Tetenev F.F. Inflammatory iactors and the state oi the microcirculatory bed in patients after low doses oi ionizing radiation // Bulletin oi New Medical Technologies. 2012. Vol. XVIII, № 2. P. 358-361. 20. Puzyrev V.P. The phenomenon-genomic relationships and pathogenetics oi multiiactorial diseases // Bulletin oi RAMS. 2011. № 9. P. 17-27. 21. Panacheva L.A., Platonova E.A., Kuznetsova G.V. The ireguency and clinical maniiestations oi the metabolic syndrome in vibration disease // Medicine oi Work and Industrial Ecology. 2011. № 10. P. 36-39. 22. Rudnitskiy V.A., Semke V.Ya., Garganeeva N.P. Non-psychotic mental disorders in conjunction with somatic diseases in liguidators oi the Chernobyl accident // Russian Journal oi Psychiatry. 2010. № 6. P.34-40. 23. Slusareva O.A., Vorontsova Z.A. The dose-effects oi single - radiation and state oi homeostasis jejunal mucous membrane in the dynamics oi prolonging the period oi observation//Bulletin oi New Medical Technologies. 2010. VoLXXVH, № 2. P. 39-41. 24. Samsonova M.V., ChernyaevAl., KopylevI.D., Chikina S.Yu. Pathological anatomy oi the lungs at the inhalation disorder oi the multicomponent dust deieat after the accident at the Chernobyl nuclear power plant in the long term // Pulmonolo-gy. 2006. № 4. P. 46-52. 25. Smulevich A.B., Dubnitskaya E.B., Tkhostov A.Sh., Zelenina E.V., Andryushchenko A.V., Ivanov S.V. Depressions and comorbid conditions / Ed. A.B. Smulevich. M.: 1997. P.28-53. 26. Telkova I.L. Features of manifestations the cardiovascular diseases among the liguidators of the accident at the Chernobyl nuclear power plant after 25 years. Clinical and analytical review // Cardiovascular Therapy and Prevention. 2012. Vol. 11, № 3. P. 62-69. 27. TorosyanEA., Torosyan A.Ts., Semerjyan V.V. «Black Hole» of medicine - polymorbidity // Bulletin of New Medical Technologies. 2008. Vol. 15, № 1. P. 202-204. 28. Chistyakov D.A., Turakulin R.I., Moiseev S.V. Polymorphism T174M angiotensinogen gene in Moscow population is associated with hypertension // Molecular Biology. 1999. Vol. 33, №4.- P. 592-594. 29. ChuchalinA.G., ChernyaevA.L, VuazenK. Respiratory diseases in liguidators of the Chernobyl accident. M.: Grant, 1998.-272 p. 30. Chikina S.Yu., Kopylev N.D., Chernyaev A.L., Sam-sonova M.V. Pashkova T.L., Chizhikov V.V., Chuchalin A.G. Features of respiratory diseases among the liguidators of the Chernobyl accident // Pulmonology. 2006. № 4. P. 33-38. 31. Shilkina N.P. Rheumatic diseases and atherosclerosis: the role of rheological and microcirculatory disturbances // Angiology and Vascular Surgery. 2010. Vol. 16, № 2. P. 23-29. 32. Shirinsky V.S. Shirinsky I.V. Comorbid diseases -an urgent problem of medicine // Siberian Journal of Medicine. 2014. Vol. 29, № 1. P. 7-12. 33. Elshteyn N.V. Present-day medical patients: Common clinical features//Russian Medical Journal. 1997. Vol. 5, № 6. P. 344-352. 34. Barabasi A.-L, Albert R., Jeong H. Mean-field Theory for Scale-free Random Networks // Physica. 1999. A 272. P. 173-187. 35. Campbell-Scherer D. Multimorbidity challenge of evidence-based medicine//Evid. Based med. 2010. Vol. 15. P. 165-166. 36. Jain K. From molecular diagnostics to personalized medicine // Expert. Rev. Mol. Diagn. 2002a. Vol. 2, № 4. P. 299-301. 37. KvetnoyL, Hernandez-Yago J., Hernandez J., Kvetnaia T.V., Reiter R.J., Khavinson V.K. Diffuse neuroendocrine system and mitochondrial diseases: molecular and cellular bases of pathogenesis, new approaches to diagnosis and therapy // Neuro Endocrinol. Lett. 2000b. Vol. 21, № 2. P. 83-99. 38. Puzyrev V.P., Makeeva O.A., Freidin M.B. Syntropy, genetic testing and personalized medicine // Personalized Medicine. 2010. Vol. 7, № 4. P. 399-405. 39. Preston D.L., Pierce D.A., Shimizu Y. et al. Effect of recent changes in atomic bombs survivor dosimetry on cancer mortality risk estimates//Radiat. Res. 2004. Vol. 162. P. 377-389. 40. Wittchen H.U. What is comorbidity - fact or artifact? //British J. of Psychiatry. 1996. Vol. 168(suppL). P. 9-16. Comments Visits: 25736 Kolesnichenko A.P., Mosyakin N.A., Raspopin Y.S., Kondrashov M.A. Informativeness of the various biochemical markers of sepsis: literary and own data Pages: 11-17 Kolesnichenko A. P., Mosyakin N. A., Raspopin Y. S., Kondrashov M. A. Informativeness of the various biochemical markers of sepsis: literary and own data. Siberian Medical Review. 2015; 4:11-17. (In Rus.). DOI 10.20333/25000136-2015-4-11-17 Authors Kolesnichenko Anatoliy Pavlovich Dr.Med.Sc, Professor of the Department of Anesthesiology and Intensive Care; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; kapitar@mail.ru Mosyakin Nilokai Antonovich ; Head oflCUNal in Regional Clinic of Maternal and Child Health; Raspopin Yuri Svyatoslavovich Postgraduate Student, Department of Anesthesiology and Itensive Care; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; oar24@mail.ru Kondrashov Maksim Andreevich Anesthesiologist; Regional Clinic of Maternal and Child Health; kondrashov.maks@gmail.com Annotation The review presents recent data on the informativeness of different biochemical markers for early diagnosis of sepsis, the most studied in detail as follows: C-reactive protein, procalcitonin, presepsin, endotoxin. Also is presented the own experience of the authors in determination of the endotoxin activity for the diagnosis of severe sepsis. Keywords: sepsis, C-reactive protein, procalcitonin, presepsin, endotoxin activity Reference List: 1. Вельков В.В. Прокальцитонин и С-реактивный белок в современной лабораторной диагностике // Клинико-лабораторный консилиум. 2009. С. 34-38. 2. Гельфанд Б.Р., Бурневич С.З., Гельфанд е.Б., Бражник Т.Б., Сергеева Н.А. Биохимические маркеры системной воспалительной реакции: роль прокальцитонина в диагностике сепсиса // Инфекция в хирургии. 2007. Т. 5, № 1. С. 17-24. 3. Гельфанд Б.Р., Проценко Д.Н., Гельфанд е.Б., Ярошецкий А.И. Сепсис: патогенез и современные методы интенсивной терапии // Руководство по экстракорпоральному очищению крови в интенсивной терапии. 2009. С. 273-299. 4. Демидова В.С., Ушакова Т.А., Звягин А.А., Бобровников А.Э., Медова О.В., Коряков И.А. Клиническая значимость пресепсина при инфекционных осложнениях у хирургических больных и пациентов с ожоговой травмой // Инфекции в хирургии. 2014. № 4. С. 44-46. 5. Иошиказу Окамура. Пресепсин – высокоэффективный диагностический маркер сепсиса // Лаборатория. 2014. № 2. С. 8-9. 6. Плющ М.Г., Самсонова Н.Н., Абрамян М.В., Попок З.В., Назарова е.И., Ступченко О.С., Ярустовский М.Б. Прогностическая значимость показателя активности эндотоксина у больных сепсисом после операций на сердце и сосудах // Инфекции в хирургии. 2011. № 2. С. 27-31. 7. Попов Д.А., Овсеенко С.Т., Вострикова Т.Ю. Прокальцитонин как предиктор бактериемии в послеоперационном периоде у кардиохирургических больных // Анестезиология и реаниматология. 2014. № 2. С. 4-9. 8. Ронко К., Пиччини П., Рознер М.Г. Эндотоксемия и эндотоксический шок. Патогенез, диагностика и лечение. М.: Издатель Балабанов И.В., 2012. 132 с. 9. Руднов В.А. Сепсис: современные подходы к диагностике и интенсивной терапии (часть первая) // Вестник анестезиологии и реаниматологии. 2010. № 7( 1). С. 48-57. 10. Савельев В.С., Гельфанд Б.Р. Сепсис в нале XXI века. Классификация, клинико-диагностическая концепция и лечение. Патологоанатомическая диагностика: практическое руководство. М.: Литера, 2006. 176 с. 11. Сепсис: классификация, клинико-диагностическая концепция и лечение: практическое руководство. 3-е изд., доп. и перераб. / Под ред. В.С. Савельева, Б.Р. Гельфанда. 2013. 350 с. 12. Ситников А.Г., Травина Л.А., Багирова В.Л. ЛАЛ-тест. Современные подходы к определению пирогенности. М., 1997. 125 с. 13. Bang F.B. A bacterial disease of Limulus Polyphemus // Bull John Hopkins Hosp. 1956. Vol. 98, № 5. P. 325-337. 14. Barati M., Alinejad F., Bahar M.A., Satar M., Tabrisi Z., Bodohi N., Karimi H. Comparison of WBC, ESR, CRP and PCT serum levels in septic and nonseptic burn cases // Burns. 2008. Vol. 34. P. 770-774. 15. Becker K.L., Shider R., Nylen E. Procalcitonin assay in systemic inflammation, infection and sepsis: clinical utility and limitations // Crit. Care Med. 2008. Vol. 36, № 3. P. 941-952. 16. Bone R.S. Sepsis: a new Hypothesis for pathogenesis of the disease progress // Chest. 1997. Vol. 112. P. 235-243. 17. Cardosso P.G., Macedo G.C., Azevedo V., Oliveira S.C. rurcellasppnoncanonical LPS: structure, biosynthesis, and interaction with host immune system // Microb. Cell Fact. 2006. Vol. 5. P. 13. 18. Ciriello V., Gudipati S., Stavrou P.Z., Kanakaris N.K., Bellamy M.C., Giannoidis P.V. Biomarkers predicting sepsis in polytrauma patients: Current evidence // Injure. 2013. Vol. 44. P. 1680-1692. 19. Dellinger R.P, Levy M.M., Rhodes A., Annane D., Gerlach H., Opal S.M., Sevranshy J.E., Sprung C.L., Douglas I.S., Jaeschke R., Osboen T.M., Nunnally M.E., Towsend S.R., Reinhart K., Kleinpell R.M., Angus D.C., Deutschman C.S., Machado F.R., Rubenfeld G.D., Webb S.A., Beale R.J., Vincent J.L., Moreno R. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock // Crit. Care Med. 2013. Vol. 41. P. 580-637. 20. Douglas G.W., Seller F.K., Debrovner C.H. The demonstration of endotoxin in the circulating blood of patients with septic abortion // Ann. J. Obstet. Gynecol. 1963. Vol. 87. P. 87-780. 21. Endo E., Takahashi G., Shozushima T., Matsumoto N., Kojika M., Suzuki Y., Inoue Y. Usefulness of Presepsin (Soluble CD14 Subtype) as a Diagnostic Marker for Sepsis // JJAAM. 2012. Vol. 23. P. 23-38. 22. Endo S., Suzuki Y., Takahashi G., Shozushima T., Ishikura H., Murai A., Nishida T., Irie Y., Miura M., Igushi H., Fukui Y., Tanaka K., Nojima T., Okamura Y. Usefulness of presepsin in the diagnosis of sepsis in multicenter prospective study // J. Infect. Chemother. 2012. Vol. 18, № 6. P. 891-897. 23. Endo S., Suzuki Y., Takahashi G., Shozushima T., Ishikura H., Mutai A., Nishida T., Irie Y., Miura M., Igushi H. Presepsin as a powerful monitoring tool for the prognosis and treatment of sepsis: A multicenter prospective study // J. Infect Chemother. 2014. Vol. 20, № 1. P. 30-34. 24. Gros A., Roussel M., Sauvadet E., Gacouin A., Margues S., Chimot L., Lavoue S., Camus C., Fest T., Le Tutzo Y. The sensitivity of neutrophil CD64 expression as a biomarker of bacterial infection is low in critically ill patients // Intensive Care Med. 2012. Vol. 38, № 3. P. 445-452. 25. Hohn A., Schroeder S., Gehrt A., Bemhardt K., Bein B., Wegscheider K. Procalcitonin-Guided Algorithm to Reduce Length of Antibiotic Therapy in Patients With Severe Sepsis and Septic Shock // BMS Infect Dis. 2013. Vol. 158. P. 13. 26. Jan-Louis V., Marijorie B., Diagnostic and Prognostic Markers in Sepsis // Expert Rev Anti Infect Ther. 2013. Vol. 11, № 3. P. 265-275. 27. Klein D., Derzko A., Foster D., Seely A.J.E., Brunet F., Romaschin A.D., Marshall J.C. Daily variation in endotoxin levels is associated with increased organ failure in critically ill patients // Shock. 2007. Vol. 28. P. 524-529. 28. Klein D., Monti G., Colombo S., Mininni M., Terzi V., Ortisi GM., Vesconi S., Casella G. Clinical asbessment does not predict endotoxemia in septic shock // Crit. Care Med. (Suppl). 2009. Vol. 37, № 12. P. 462. 29. Kojika M., Takahashshi G., Matsumoto N., Kikkawa T., Hoshikawa K., Shioya N. Serum levels of soluble CD14 subtype reflect the APACHE II and SOFA scores // Med. Postgrad. 2010. Vol. 48. P. 46-50. 30. Kulabukhov V. The use of an endotoxin adsorption in the treatment ofsevere abdominal sepsis // Acte Anaesthesiol. Scan. 2008. Vol. 52, № 7. P. 1024-1025. 31. Liu B., Chen Y.X., Yin Q., Zhao V.Z., Li C.S. Diagnosnostic value and prognostic evaluation of Presepsin for sepsis in an emergency department // Crit Care. 2013. Vol. 17, № 5. P. 244. 32. Lobo S.M., Lobo F.R., Bota D.P., Lopes-Ferreira F., Solman H.M., Melot C., Vincent J.L. C-reactive protein levels correlate with mortality and organ failure in criticalle ill patients // Chest. 2003. Vol. 123, № 6. P. 2043-2049. 33. Marshall J., Foster D., Vincent J., Cook D.J., Dellinger R.P., Opal S., Abraham E. Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study // J. Infect. Dis. 2004. Vol. 190. P. 527-534. 34. Masson S., Caironi P., Spanuth E., Thomae R., Panigada M., Sangiorgi G., Fumagalli R., Mauri T., Isgro S., Fanizza C., Romero M. Presepsin (soluble CD14 subtype) and procalcitonin levels for mortality prediction in sepsis: data from the Albumin Italian Outcome Sepsis trial // Crit. Care. 2014. Vol. 18, № 1. P. 64. 35. Nobre V., Harbath S., Graf J.D., Rohner P., Pugin J., Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial // Am. J. Respir. Crit. Care Med. 2008. Vol. 177, № 5. P. 498-505. 36. Pepus M.B., Hirschfield G.M. C-reactive protein: a critical update // J. Clin. Invest. 2003. Vol. 111. P. 1805-1812. 37. Pierrakos C., Vincent J. L., Sepsis biomarkers: a review // Crit. Care. 2010. Vol. 14, № 1. P. 15. 38. Povoa P., Coelho L., Almeida E.,Femandes R., Mealha P., Moreira H., Sabino S. Early identification of intensive care unitacquired infection with daily monitoring of C-reactive prorein: a prospective observational study // Crit. Care. 2006. Vol. 10, № 2. P. 63. 39. Romaschin A.D., Harris D.M., Ribeiro M.B., Paice J., Foter D.M., Walker P.M., Marshall J.C. A rapid assay of endotoxin in whole blood using autologous neutrophil dependent chemiluminescence // J. Immunol. Methods. 1998. Vol. 212. P. 169-185. 40. Schuetz P., Christ-Crain M., Muller E. Biomarkers to improve diagnostic and prognostic accuracy infections // Curr. Opin. Crit. Care. 2007. Vol. 13, № 5. P. 578-585. 41. Tillett W.S., Francis T. Serological reactions in pneumonia with a non-protein somatic fraction of Pneumococcus // J. Exp. Med. 1930. Vol. 52, № 4. P. 561-571. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25687 Mordyk A.V., Puzyreva L.V., Kravchenko E.N., Valeeva G.A. The influence of pregnancy to the specific process in the lungs Pages: 18-23 Mordyk A. V., Puzyreva L. V., Kravchenko E. N., Valeeva G. A. The influence of pregnancy to the specific process in the lungs. Siberian Medical Review. 2015; 4:18-23. (In Rus.). DOI 10.20333/25000136-2015-4-18-23 Authors Mordyk Anna Vladimirovna Dr.Med.Sc, Associate Professor Head of the Department of Phthisiology and Phthisiosurgery; Omsk State Medical University; amordik@mail.ru Puzyreva Larisa Vladimirovna Cand.Med.Sc, Assistant of the Department of Phthisiology and Phthisiosurgery; Omsk State Medical University; puzirevalv@mail.ru Kravchenko Elena Nikolaevna Dr.Med.Sc, Associate Professor, Head of the Department of the Obstetrics and Gynecology of PE; Omsk State Medical University; kravchenko.en@mail.ru Valeeva Galina Aleksandrovna Postgraduate Student of the Department of Obstetrics and Gynecology ofPE; Omsk State Medical University; missgalin@mail.ru Annotation The article presents an analysis of published data on the problem of influence the pregnancy to the specific process in the lungs, prepared within the framework of the grant RHF «Social aspects of interaction the problems of reproductive health and tuberculosis» State Registration № 115042210032 2015. The greatest number of authors point to the negative influence of pregnancy to tuberculosis, which is expressed in its progression or exacerbation. However, part of the publication provides information on the possible favorable outcome of tuberculosis in pregnant in conditions of full chemotherapy. Analysis of available publications shows the need for research uniting the scattered material on the issue from the different regions, the creation of a single register of these patients to determine the tactics of the treatment in each particular case Keywords: tuberculosis, pregnancy, termination of pregnancy, postpartum, social factors Reference List: 1. Actual guestions of tuberculosis: Textbook / Ed. V.G. Kononenko. Ed. 2nd. Novosibirsk, 2006. 90 p. 2. BogadernikovaI.V.,PungaVV Organization of ТВ care at the municipal level. Health education of patients and their relatives. M.: CPU Rainbow, 2006. 30 p. 3. ValievR.Sh., GilyazutdinovaZ.Sh. Tuberculosis and pregnancy: methodical manual. Kazan: Medicine, 2000. 85 p. 4. Viezel A.A., GurylevaM.E. Tuberculosis. M., Medicine, 1999. 208 p. 5. Glazkova I.V., Volkova E.N., Molchanova L.F. Risk factors for tuberculosis in women of reproductive age // Problems of Tuberculosis and Lung Disease. 2010. №4. P. 23-26. 6. Gulua I.R., Zhuchenko O.T., Semykina N.G. Features of ovarian function in women with different localizations of tuberculosis // Bulletin of the Russian Association of Obstetricians and Gynecologists. 2002. № 2. P. 16-20. 7. Zhuchenko O.G., Gabarnik A.E., Kurnosova I.S., Aidamirova R.M., Zangieva Z.A. Reproductive health in women with tuberculosis // Tuberculosis and Lung Disease. 2011.- Vol. 88, №4. P. 148. 8. Zhuchenko O.G., Radzinsky V.E. Reproductive health of women with pulmonary and urogenital tuberculosis // Problems of Tuberculosis and Lung Disease. 2004. № 7. P. 58-62. 9. IlyinaT.Ya., MuminovTA., KaldybaevS.K. Tuberculosis of the respiratory organs and effectiveness of its treatment in certain high-risk groups // Problems of Tuberculosis and Lung Disease. 2000. №4. P. 9-11. 10. Kayukova S.I., Stakhanov V.A., Makarov O.V. Pregnancy and tuberculosis - the current state of the problem // Problems of Tuberculosis and Lung Disease. 2003. №9.-P. 31-35. 11. Clinical lectures on phthisiology:: The lecture course. Part II / ed. T.P. Maslauskene. Irkutsk, 2006. 109 p. 12. Kovganko P.A. On the problem of tuberculosis and maternal // Problems of Tuberculosis and Lung Disease. 2003. № 4. P. 46-48. 13. Kovganko P.A., Evstigneev S.V., Petrukhin V.A. The course of pregnancy and childbirth in women with pulmonary tuberculosis // Russian Bulletin of the Obstetrician-Gynecologist. 2005. Vol. 5, № 2. P. 24-26. 14. Kolachevskaya E.N., Vorotynova N.A., Tyutikova T.I. Tuberculosis and pregnancy // Problems of Tuberculosis and Lung Disease. 1994. №5. P.48-51. 15. Koretskaya N.M. Age and sex characteristics of newly diagnosed pulmonary tuberculosis in the Krasnoyarsk region // Problems of Tuberculosis and Lung Disease. 2007. №7.-P. 7-11. 16. Koretskaya N.M. Clinical and social aspects of pulmonary tuberculosis in young women // Problems of Tuberculosis and Lung Disease. 2002. № 11. P. 4-5 17. Koretskaya N.M. Tuberculosis, pregnancy and motherhood//Mother and Child in the Kuzbass. 2012. Vol.48, №1.-P. 12-19. 18. Koretskaya N.M., Bolshakova LA., Zagorulko O.V. Tuberculosis and risk factors for its development in children of Krasnoyarsk // Siberian Medical Review. 2011. Vol. 72, № 6. P. 64-67. 19. Koretskaya N.M., Narkevitch A.N., Narkevitch A.N. Gender features of newly diagnosed infiltrative lung tuberculosis// Pulmonology. 2014. № 1. P. 77-80. 20. Kravchenko E.N., Mordyk A.V., Valeyeva G.A., Puzyreva L. V. Anemia and hemostasis in pregnant women with active and clinically healed pulmonary tuberculosis // Russian Bulletin of Obstetrician-Gynecologist. 2014. Vol.14, № 6. P. 55-59. 21. Kravchenko E.N., Mordyk A.V., Valeyeva G.A., Puzyreva L.V. Features of pregnancy in women with a history of tuberculosis // Life without dangers. Health. Prevention. Longevity. 2014. № 1. P. 70-76. 22. Lysov A.V., Antropova V.V., Mordyk A.V., Ivanova O.G. The effectiveness of treatment for tuberculosis in the background of pregnancy // Omsk Scientific Bulletin. 2006. Vol. 37, №3. P. 185-188. 23. Maiseenko D.A., Egorova A.T. Features of pregnancy and delivery in women with a tuberculosis process surgery on lungs // Mother and Child in the Kuzbass. 2010. №2(41).- P. 34-35. 24. Mordyk A.V., Batishcheva T.L., Bryukhanova N.S., Puzyreva L.V. Influence oi immunological disorders on the outcome of newly diagnosed infiltrative tuberculosis in socially intact patients // Infection and Immunity. 2014 - Vol. 4, №4.-P. 353-358. 25. Mordyk A.V., Bryukhanova N.S., Antropova V.V., Puzyreva L.V. The role of the individual patient in the process of detection and treatment of pulmonary tuberculosis // Kuban Research Medical Bulletin. 2011. Vol. 127,№4. P. 148-151. 26. Mordyk A.V., Puzyreva L.V., Aksyutina L.P. The modern international and national concepts of ТВ control // Far East Journal of infectious diseases. 2013. № 22 (22). P. 92-97. 27. Mordyk A.V., Tsygankova E.A., Puzyreva L.V., Pod-kopaeva T.G., Turitsa A.A. Risk factors for tuberculosis in children (review) // Life without dangers. Health. Prevention. Longevity. 2014. № 1. P. 92-98. 28. Muminov T.A., Seydakhmetova K.S., Kozhabayeva K.M., Iskanov U.I. Pulmonary tuberculosis in young women // Problems of Tuberculosis. 1990. № 9. P. 69-70. 29. On approval of the provision of medical care to patients with tuberculosis (as on 30.12.2014): Order dated November 15, 2012 N 932n / Russian Ministry of Health // Consultant-Plus: reference legal system. Mode of access: http: // www. consultant.ru/ Date of appeal: 05.02.2015. 30. Polevaya S.P. Influence of tuberculosis intoxication on reproductive function of women of different age groups //Reproduction. 2006. №2. P. 13-15. 31. Savula M.M. The results of treatment, pregnancy and childbirth in women with operations for tuberculosis // Hospital Surgery. 2005. № 2. P. 62-64. 32. Savula M.M., Sahelashvili M.I. The freguency of drug-resistant tuberculosis and the effectiveness of its treatment in pregnant women//Practical Medicine. 2005. № 1. P. 41-44. 33. Skvortsova M.A. The identification, medical examination and effective treatment of pregnant women with pulmonary tuberculosis // Bulletin of the National Research Institute of Public Health. 2006. № 8. P. 72-74. 34. Trunov A.N., Yakimova A.V., Shvayuk A.P., Gorbenko O.M., Anisimova N.I., Shkurupiy V.A., Trunov a L.A. Some features of the immune response at the pulmonary tuberculosis in pregnant // Allergology and Immunology. 2007. Vol. 8, №2.-P. 110-112. 35. Tuberculosis in children and adolescents: a guide / Ed. E.N. Yanchenko, M.S. Greymer. Ed. 2nd, Revised, and add.-SPb., 1999.-336 p. 36. Tuberculosis in children and adolescents: a guide / Ed. O.I. KoroL, M.E. Lazovsky. SPb., 2005. 432 p. 37. Tuberculosis in children and adolescents: the Manual / Under. Ed. L.B. Khudzik, E Ya. Potapova, E.N. Alexand-rova. M.: Medicine, 2004. 386 p. 38. Fedotova Z.N. Treatment of pulmonary tuberculosis in pregnancy:guidelines. M.:Medicine, 1969. 123p. 39. Fisher Yu.Ya. Pregnancy and childbirth as risk factors for tuberculosis // Problems of Tuberculosis and Lung Disease. 1994. № 14. P. 14-17. 40. Chebotareva T.V. On the issue of tuberculosis and maternity // Problems of Tuberculosis and Lung Disease. 1990. №11. P. 6-7. 41. Chushkina A.A., Koretskaya N.M. Pathomorphosis of the infiltrative pulmonary tuberculosis for 20 years // Bulletin of the East Siberian Scientific Center of the SB RAMS. 2012. Vol. 87, №5.-P. 141-144. 42. Yakimova A.V., Trunov A.N., Shvayuk A.P., Gorbenko O.M., Shkurupy V.A. Features of the immuno-inflammatory processes and perinatal outcomes in pulmonary tuberculosis in pregnant//Surgery. Morphology. Lymphology. 2006. Vol.3, №6.-P. 7-10. 43. Bothamley G. Drug treatment for tuberculosis during pregnancy: safety considerations // Drug. Saf. 2001. T. 24, № 7. С 553 -565. 44. Lessnau K.D., Qarah S. Multidrug-resistant tuberculosis in pregnancy: case report and review of the literature // Chest. 2003. Vol. 123, № 3. P. 953-956. 45. Vo Q.T., Stettler W., Grawley K. Pulmonary tuberculosis in pregnancy // Prim. Care Update Obstet. Gynecol. 2000.-Vol.7, №1. P. 244-249. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25706 Lapteva L. V. The iron deficiency and helicobacter pylori infection in children. Siberian Medical Review. 2015; 4:24-29. (In Rus.). DOI 10.20333/25000136-2015-4-24-29 Authors Lapteva Lyudmila Vladimiroma Cand.Med.Sc, Leading Researcher of the Laboratory of Mental Health and Social Adaptation; Federal State Budgetary Institution Scientific Research Institute of Medical Problems of the North; prale@list.ru Annotation Infection Helicobacter pylori (HP) is very common among the general population. It is proved that HP causes not only diseases of the stomach, but also has non-gastral manifestations. There is evidence of involvement ofH pylori infection in the development of iron deficiency and iron deficiency anemia, which affects mostly to the pediatric population. It is the most common nutritional deficiency in the world that has a negative impact on health and impact on the overall level of mortality from IDA. Perhaps there are several mechanisms that explain the relationship pathogenic infection and the decline in iron metabolism. Proven participation role of H. pylori infection in the development of children WDN enables purposeful implementation of measures to reduce the spread of infection and reduce HP iron deficiency in high-risk groups. Keywords: Helicobacter pylori, children, iron, anemia Reference List: 1. Kornienko E.A.Outside stomach manifestations of Helicobacter pylori infection in children // Gastroenterology. 2009.-№ 1. P. 67-69. 2. Polivanova T.V., Manchuk V.T., Vshivkov V.A., Gon-charova M.V. Helicobacter pylori infection prevalence and its association with clinical and morphological manifestations of gastroduodenal pathology in children of ethnic populations in Tyva // Pediatrics. 2013. Vol. 92, № 6. P. 135-140. 3. Rumyantsev A.G., Tarasova I.S., Chernov V.M. Iron deficiency states: causes, diagnostic and treatment // Institute of Pediatric Hematology, Ministry of Health of the Russian Federation in Moscow. 2006 [Electronic resource]. Access: http://www.medic-21vek.ru/lekc/detail.php?ID = 1792. 4. Statistical information «Morbidity of the population in Russia.» [Electronic resource]. Access: http://www.min-zdravsoc.ru/docs/mzsr/stat/. 5. Tereshchenko S.Y., Lapteva L.V. Iron metabolism in adolescent girls when Helicobacter pylori- associated chronic gastritis // The Questions of Children Nutrition. 2013. Vol. 11, №1. P. 24-29. 6. Ursova N.I. Helicobacter pylori infection in children: the problem, the analysis of generalized data. M., 2009. 78 p. 7. Fadeenko G.D. Helicobacter pylori and out of stomach manifestations // Ukrania Therapeutic Journal. 2004. № 2. P. 95-99. 8. Hurtl M. Differential diagnosis in pediatrics: in 2 Volumes / M. Hurtle; Transl. from German by M.A. Karachunsky, N.S. Kantanistova. M.: Medicine, 1990. P. 57. 9. Zimmerman Ya.S. Helicobacter pylori-infection: out of stomach effects and diseases (critical analysis) // Clinical Medicine. 2006. № 4. P. 63-67. 10. ShcherbakovP.L, PotapovA.S., DublinaE.S., Shcherbak-ovaM.Yu., SamsyginaGA., ErdesS.L, LogvinovaAI., Kudryavt-seva L.V. Schemes of eradication the strains Helicobacter pylori, resistant to metronidazole in children //Questions of Current Pediatrics. 2007. №6:5. P. 100-104. ll.BaggettH.C, Parkinson A.J., Muth P.T., Gold B.D., GessnerB. D. Endemic Iron Deficiency Associated With Helicobacter pylori Infection Among School-Aged Children in Alaska //Pediatrics. 2006. Vol. 117, № 3.-P. 396-404. 12. Barabino A. Helicobacter pylori-related iron deficiency anemia: a review// Helicobacter. 2002. Vol. 7, №2. P. 71-75. 13. Berg G., Bode G., Blettner M., Boeing H., Brenner H. Helicobacter pylori infection and serum ferritin: a population-based study among 1,086 adults in Germany //Am. J. Gastroenterol. 2001. Vol. 96. P. 1014-18. 14. Bini EJ. Helicobacter pylori and iron deficiency anemia: guilty as charged? //Am. J. Med. 2001. Vol.111. P. 495-497. 15. Cardenas V.M., Mulla Z.D., Ortiz M., Graham D.Y. Iron deficiency and Helicobacter pylori infection in the United States //Am. J. Epidemiol. 2006.-Vol. 163. P. 127-134. 16. Choi J.W. Does Helicobacter pylori infection relate to iron deficiency anaemia in prepubescent children under 12 years of age?//Acta Paediatr. 2003. Vol.92. P. 970-972. 17. Choe Y.H., Kwon Y.S., Jung M.K., Kang S.K., Hwang T.S., HongY.C. Helicobacter pylori-associated iron-deficiency anemia in adolescent female athletes//J. Pediatr. 2001. Vol. 139. P. 100-104. 18. Clark S.F. Iron deficiency anemia: diagnosis and management // Curr. Opin. Gastroenterol. 2009. Vol. 25. P. 122-128. 19. DuBois S., Kearney D.J. Iron-deficiency anemia and Helicobacter pylori infection: a review of the evidence //Am. J. Gastroenterol. 2005. Vol. 100. P. 453-459. 20. Gasbarrini A., Franceschi F., Armuzzi A., Ojetti V.., CandelliM., Sanz Torre E., De Lorenzo A., AntiM., Pretolani S., Gasbarrini G. Extradigestive manifestations of Helicobacter pylori gastric infection//Gut. 1999.-Vol.45,№l. P. 9-12. 21. Gasche C, Lomer M.C., Cavill I., Weiss G. Iron, anaemia, and inflammatory bowel diseases // Gut. 2004. Vol.53.-P. 1190-1197. 22. HowdenC.W., Hunt R.H. Guidelines forthe management of Helicobacter pylori infection. Ad Hoc Committee on Practice Parameters of the American College of Gastroenterology//Am. J. Gastroenterol. 1998.-Vol. 93. P. 2330-2338. 23. Huang J.Q., Sridhar S., Hunt R.H. Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis // Lancet. 2002. Vol.359.-P. 14-22. 24. Jolobe O. Guidelines for the management of iron deficiency anaemia//Gut. 2001. Vol. 49. P. 158. 25. Kearney D.J., Ioannou G.N., The association between Helicobacter pylori seropositivity and serum markers of iron stores in the United States. (Abstract W952). Presented at 2005 Digestive Disease Week, Chicago, Illinois, 2005. P. 72 26. Kurekci A.E., AtayAA, SariciS.U., YesilkayaE., Senses Z., Okutan V., Ozcan O. Is there a relationship between childhood Helicobacter pylori infection and iron deficiency anemia ? //J. Trop. Pediatr. 2005. Vol.51. P. 166-169. 27. Malfertheiner P., Megraud F., OMorain C, Bazzoli F., El-Omar E., Graham D., Hunt R., Rokkas Т., Vakil N., Kuipers EJ. Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report // Gut. 2007.-Vol.56.-P. 772-781. 28. Milman N., Rosenstock S., Anderson L., Jorgensen Т., Bonnevie O. Serum ferritin, hemoglobin, and Helicobacter pylori infection: a seroepidemiologic survey comprising 2,794 Danish adults//Gastroenterology. 1998.-Vol. 345. P. 1525-1528. 29. Parkinson A.J., Gold B.D., Bulkow L, Wainwright R.B., Swaminathan В., Khanna В., Petersen K.M., Fitzgerald M.A. High prevalence of Helicobacter pylori in the Alaska native population and association with low serum ferritin levels in young adults // Clin. Diagn. Lab. Immunol. 2000. Vol. 7. P. 885-888 30. Peterson W.L., Fendrick A.M., Cave D.R., Peura D.A., Garabedian-Ruffalo S.M., Laine L. Helicobacter pylori-related disease: guidelines for testing and treatment //Arch Intern Med. 2000. Vol. 160. P. 1285-1291. 31. Ramakrishnan U. Prevalence of micronutrient malnutrition worldwide//Nutr Rev. 2002. Vol.60. P. 46-52. 32. Ruiz В., Rood J.C., Fontham E.T., Malcom G.T., Hunter F.M., Sobhan M., Johnson W.D., Correa P. Vitamin С concentration in gastric juice before and after anti-Helicobacter pylori treatment//Am. J. Gasroenterol. 1994.-Vol. 89. P. 533-539. 33. Russo-Mancuso G., Branciforte F., Licciardello M., La Spina M. Iron deficiency anemia as the only sign of infection with Helicobacter pylori: a report of 9 pediatric cases //Int. J. Hematol. 2003. Vol. 78. P. 429-431. 34. Seo J.K., Ко J.S., Choi K.D. Serum ferritin and Helicobacter pylori infection in children: a sero-epidemiologic study in Korea // J. Gastroenterol. Hepatol. 2002. Vol. 17. P. 754-757. 35. Suerbaum S., Michetti P. Helicobacter pylori infection //N.Engl. J. Med. 2002.-Vol. 347. P. 1175-1186. 36. Veres G., Pehlivanoglu E. Helicobacter pylori infec-tiontrics in pediatrics // Helicobacter. 2007. Vol. 12. (S. 1). P. 38-44. 37. Weiss G., Goodnough L.T. Anemia of chronic disease //N.Engl. J. Med. 2005.-Vol. 352. P. 1011-1023. 38. Weyermann M., Rothenbacher D., Gayer L, Bode G., Adler G., Grab D., Flock F., Brenner H. Role of Helicobacter pylori infection in iron deficiency during pregnancy //Am. J. Obstet. Gynecol. 2005.-Vol. 192. P. 548-553. 39. Wong B.C., Lam S.K., Wong W.M., Chen J.S., Zheng T.T., Feng R.E., Lai K.C., Hu W.H., Yuen ST., Leung S.Y., Fong D.Y., Ho J., Ching C.K., Chen J.S. Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial // JAMA. —2004. — Vol. 291.-P. 187-194. 40. World Gastroenterology Organisation. WGO Practice Guideline: Helicobacter pylori in Developing Countries. URL: http://www.worldgastroenterology.org/assets/downloads/en/ pdf/guidelines/11_helicobacter_pylori_developing_coun-tries_en.pdf, accessed 2005. 41. World Health Organization, United Nations University, The United Nations Childrens Fund. Iron deficiency anaemia. Assessment, prevention and controLA guide for programme managers. URL: http://whglibdoc.who.int/hg/2001/WHO_ NHD_0L3.pdf, accessed 2001. 42. World Health Organization. Micronutrient deficiencies-Iron deficiency anaemia. URL: http://www.who.int/nutrition/ topics/ida/en/index.html, accessed 2001. 43. World Health Organization, The United Nations Childrens Fund, United Nations University. Iron deficiency anaemia: assessment, prevention, and control. URL: http://www.who.int/ nut/documents/ida_assessment_ prevention_control.pdf, accessed 27 July, 200424. 44. Zhang Z.W., Patchett S.E., Perett D., Katelaris P.H., Domizio P., Farthing MJ. The relation between gastric vitamin С concentrations, mucosal histology, and CagA seropositivity in the human stomach//Gut. 1998.-Vol. 43. P. 322-326. 45. Zimmermann M.B., Hurrell R.F. Nutritional iron deficiency//Lancet. 2007.-Vol. 370. P. 511-520. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25688 Sobko E.A., Demko I.V., Kraposhina A.Y., Egorov S.A., Vtyurina S.S., Solovjeva I.A., Ishchenko O.P., Gordeeva N.V., Chubarova S.V. The level of adipocines in peripheral blood of young patients with bronchial asthma Pages: 29-33 Sobko E. A., Demko I. V., Kraposhina A. Yu., Egorov S. A., Vturina S. S., Soloveva I. A., Ischenko O. P., Gordeeva N. V., Chubarova S. V. The level of adipocines in peripheral blood of young patients with bronchial asthma. Siberian Medical Review. 2015; 4:29-33. (In Rus.). DOI 10.20333/25000136-2015-4-29-33 Authors Sobko Elena Albertovna Dr. Med. Sc, Assotiated Professor, Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; sobko29@mail.ru Demko Irina Vladimirovna Dr.Med.Sc, Professor, Head of the Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; 660022, Красноярск, ул. Партизана Железняка, 1; e-mail: demko64@ mail.ru Kraposhina Angelina Yurievna Cand.Med.Sc, Assistant of the Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; angelina-maria@inbox.ru Egorov Stepan Alexandrovich Assistant of the Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; dlyavsego89@mail.ru Vtyurina Svetlana Sergeevna Intern of the Department of Internal Diseases № 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; elma-06@mail.ru Solovjeva Irina Anatolyevna Cand.Med.Sc, Assistant, Department of Internal Diseases N2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; solovieva.irina@inbox.ru Ishchenko Olga Petrovna Cand.Med.Sc.,; Krasnoyarsk regional hospital (Krasnoyarsk); fridag@yandex.ru Gordeeva Natalia Vladimirovna Cand.Med.Sc., Assistant, Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; natagorday@yandex.ru Chubarova Svetlana Vladimirovna Cand.Med.Sc, Assistant of the Department of Internal Diseases N 2; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; svetachubarova@mail.ru Annotation The aim of the research. To study clinical - functional features in conjunction with the level ofleptin and adiponectin in the syntropy В A and alimentary obesity in young people in order to optimize anti-asthmatic therapy. Materials and methods. There were examined 133 people: 93 patients with asthma were divided into 2 groups according to body mass index (BMI) and 40 healthy volunteers. All assessed the presence of overweight and determination of the degree of obesity. Determination ofleptin and adiponectin in peripheral blood plasma produced by enzyme-linked immunosorbent assay eBioscience (USA). Results. It was noted decrease in the level of adiponectin in peripheral blood in the test groups in comparison to the control. Were identified gender differences in the level ofleptin in the peripheral blood of both groups. Conclusion. One of the important pathogenetic mechanisms in syntropy asthma and obesity is an imbalance of adipokines in the blood plasma, so elevated levels ofleptin contributes to the worsening of bronchial obstruction and systemic inflammation, which reguires a differentiated approach in achieving asthma control in these patients. Keywords: bronchial asthma, obesity, leptin, adiponectin, systemic inflammation. Reference List: 1. Астафьева Н.Г., Гамова И.В., Удовиченко е.Н., Перфилова И.А. Ожирение и бронхиальная астма // Лечащий врач. 2014. № 4. С. 8-13. 2. Бойков В.А., Кобякова О.С., Деев И.А.,Куликов е.С., Старовойтова е.А. Состояние функции внешнего дыхания у пациентов с ожирением // Бюллетень сибирской медицины. 2013. № 1 (12). С. 86-92. 3. Собко е.А., Соловьева И.А., Ищенко О.П., Крапошина А.Ю., Демко И.В., Чубарова С.В., Павлова Н.Ю. Изменение цитокинового профиля крови у больных бронхиальной астмой тяжелого течения с ожирением // Российский аллергологический журнал. 2013. № 6. С. 13-20. 4. American Lung Association Asthma Clinical Research Centers. Clinical trial of low-dose theophylline and montelukast in patients with poorly controlled asthma // Am. J. RespirCrit Care Med. 2007. № 175. P. 235-242. 5. Carbone F., La Rocca C., Matarese G. Immunological functions of leptin and adiponectin // Biochimie. 2012. Vol. 94, № 10. P. 2082-2088. 6. Dixon A.E. Adipokines and asthma //Chest. –2009. Vol. 135. P. 255-256. 7. Leiria L.O., Martins M.A., Saad M.J. Obesity and asthma: beyond T(H)2 inflammation // Metabolism. 2015. –Vol. 64, № 2. Р. 172-181. 8. Mancuso P., Canetti C., Gottschalk A., K. Tithof P., Peters-Golden M. Leptin augments alveolar macrophage leukotriene synthesis by increasing phospholipase activity and enhancing group IVC iPLA2 (cPLA 2.) protein expression // American Journal of Physiology-Lung Cellular and Molecular Physiology. 2004. Vol. 287, № 3. P. 497-L502. 9. Nigro E., Daniele A., Scudiero O., Ludovica M.M., Roviezzo F., D’Agostino B., Mazzarella G., Bianco A. Adiponectin in Asthma: Implications for Phenotyping // Curr. Protein Pept. Sci. 2015. № 16 (3). P. 182-187. 10. Ruhl C.E., Everhart J.E. Leptin concentrations in the United States: relations with demographic and anthropometric measures // American Journal of Clinical Nutrition. 2001. Vol. 74. P. 295-301. 11. Vortmann M., Mark D.E. BMI and Health Status Among Adults With Asthma // Obesity. 2008. Vol. 16, № 1. P. 146-152. 12. Woo H.-J., Yoo W.J., Bae C.H., Song S.Y., Kim Y.W., Park S.Y., Kim Y.D. Leptin up-regulates MUC5B expression in human airway epithelial cells via mitogen-activated protein kinase pathway // Experimental Lung Research. 2010. Vol. 36, № 5. P. 262-269. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25665 Matyskina N.V., Taranushenko T.E. Morphological characteristics of placenta in pregnant women with syphilis infection Pages: 34-38 Matyskina N. V., Taranushenko T. E., Prokhorenkov V. I. Morphological characteristics of placenta in pregnant women with syphilis infection. Siberian Medical Review. 2015; 4:34-38. (In Rus.). DOI 10.20333/25000136-2015-4-34-38 Authors Matyskina Natalya Vladimiroma Cand.Med.Sc, Assistant of the Department of Ambulatory Pediatrics and Propaedeutics of Children Diseases; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; mnv72@mail.ru Taranushenko Tatyana Evgenyevna Dr.Med.Sc, Professor, Head of the Department of Pediatrics; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; tetar@rambler.ru Annotation The aim of the research. To identify the most important histological changes of the placenta, that accompany syphilitic infection. Results. Degenerative changes in the forms of petrificates were detected in women of Till groups in 21,4-28,9%. Inflammation of the placenta were determined with a significantly higher freguency in I group. A significant prevalence of pathological changes in the placenta villous stroma were found in Till groups compared with the control. Conclusion. Leading macro- and microscopic pathological disorders of the placenta that accompany syphilitic infection were implicated in the development of complications during pregnancy and childbirth. Keywords: pregnant woman, placenta, pathological changes Reference List: 1. Izmestyeva K.A., Shabunina-Basok N.R. Adaptive and compensatory reactions of fetoplacental complex // Archives of Pathology. 2010. № 6. P. 25-27. 2. Kiseleva N.I. Morphohistologic features of placenta in pregnancy, complicated by gestosis // Mother and Child in the Kuzbass. 2012. № 1 (1). P. 39-43. 3. KulakovV. I., Ordzhonikidze N.V., Tyutyunnik V.L. Placental insufficiency and infection. M.: Medicine, 2004. 494 p. 4. Milovanov A.P. The pathology of the mother-placenta-fetus system: Guide for the Physicians. M.: Medicine, 1999.-448 p. 5. PavlovT.V., DubovaE.A., ShchegolevA.I. Fetoplacental angiogenesis in normal pregnancy: the role of vascular endothelial growth factor // Obstetrics and Gynecology. 2011. №3.-P. 11-16. 6. Prokhorenkov V.L, Maksimov A.S., Obukhov A.P. Modern views on the immune changes in syphilis // Siberian Medical Review. 2014. № 4 (88). P. 20-27. 7. StrizhakovA.N., Lipatov I.S., TezikovYu.V. Comprehensive assessment of the severity of chronic placental insufficiency //Obstetrics and Gynecology. 2012. №3. P. 20-25. 8. Taranushenko Т.Е., Matyskina N.V. Clinical manifestations of early congenital syphilis in the neonatal period // Current Pediatrics. 2006. № 5. P.372. 9. Tezikov Yu.V., Lipatov I.S. Prediction and diagnosis of severe placental insufficiency // Obstetrics and Gynecology. 2012.-№ 1. P. 35-42. 10. FilippovO.S. Placental insufficiency. M.:MEDpress-Inform, 2009. 160 p. 11. Neerhof M.G., Thaete L.G. The fetal response to chronic placental insufficiency// Semin. Perinatol. 2008. Vol. 32, №3. P.201-205. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25674 Ovchinnikova S.A., Aljamovsky V.V., Duzh A.N. Characteristics of the indicators in microhardness of the light-curing composites under different protocols at polymerization Pages: 39-41 . DOI 10.20333/25000136-2015-4-39-41 Authors Ovchinnikova Setlana Anatolyema Cand. Med. Sc, Associate Professor of the Dentistry Department ofPost-Graduate Educationlnstitute; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; narikova@inbox.ru Aljamovsky Vasiliy Viktorovich Dr. Med. Sc, Professor, Head of the Dentistry Department of Post-Graduate Education lnstitute; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; alvas.1962@mail.ru Duzh Anatoliy Nikolayevich Cand. Med. Sc, Associate Professor of the Dentistry Department of Post-GraduateEducationInstitute; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; anduzh@yandex.ru Annotation The aim of the research. Comparative evaluation of indicators changes in microhardness of the light-curing composite material of different enamel shades depending on the time of polymerization using dental photo-polymerization halogen type device. Materials and methods. Were examined the indicators in microhardness by Vickers Hardness (HV) of samples of the light-curing microhybrid composite material «Charisma Opal» (Germany) enamel shades: Al, A2, A3. Results. Indicators HV in face were higher in contrast to the back surface of the samples (p = 0.000), except shade A2. Conclusion. It is established that the photopolymerization period has the great influence to the indicator of microhardness composites. Keywords: dental photo-polymerization device, microhardness, composites Reference List: 1. AlyamovskyV.V., DuzhA.N., Kurochkin V.N., Bakashvili N.T. Polymerization possibilities of dental photo-polymerization devices diode type // Siberian Medical Review. 2009. №5.-P. 61-65. 2. Giorgi M.C., Lima D.A, Marchi G.M., Ambrosano G.M., Aguiar F.H. Influence of softening test and light-activation protocols on resin composite polymer structure // Eur. J. Dent. 2014. Vol. 8, № 1. P. 9-14. 3. Giorgi M.C., Theobaldo J., Lima D.A., Marchi G.M., Ambrosano G.M., Aguiar F.H. Influence of successive light-activation on degree of conversion and knoop hardness of the first layered composite increment // Acta Odontol. Scand. 2015. Vol. 73, № 2. P. 126-131. 4. Karaman E., Tuncer D., Firat E. Influence of different staining beverages on color stability, surface rounghness and microhardness of silorane and methacrilate-based composite resins//J. Contemp. Dent. Pract. 2014. Vol. 15, № 3. P. 319-325. 5. Pieniak D., Niewczas A.M., Walczak M., Zamoscinska J. Influence of photopolymerization parameters on the mechanical properties of polymer-ceramic composites applied in the conservative dentistry // Acta Bioeng. Biomech. 2014. Vol. 16, № 3. P. 29-35. 6. Son S.A., Roh H.M., Hur В., Know Y.H., Park J.K. The effect of resin thickness on polymerization characteristics of silorane-based composite resin // Restor. Dent. Endod. 2014. Vol. 39, №4. P. 310-318. 7. Tarle Z., Attin Т., Marovic D., Andermatt L, Ristic M., Taubock T. Influence of irradiation time on subsurface degree of conversion and microhardness of high-viscosity bulk-fill resin composites // Clin. Oral Investig. 2015. Vol. 19, №4. P.831-840. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25664 Sled N.Y., Cherdantsev D.V., Popov A.E., Merzlikin N.V., Pozdnyakov A.A., Sled O.N. Remote results of surgical treatment of chronic cystic pancreatitis Pages: 42-46 . DOI 10.20333/25000136-2015-4-42-46 Authors Sled Nikolay Yuryevich Head ofthe Surgical Department of the Nubicipal Clinical Hospital № 20 named after I. S. Berzon; Clinical Hospital № 20 named after I. S. Berzon; nsled@bk.ru Cherdantsev Dmitry Vladimirovich Dr. Med. Sc, Professor; Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; gs7@mail.ru Popov Alexander Evgenyevich Cand.Med.Sc, Associate Professor of the Department and Clinic of Surgical Diseases named after Professor A. M. Dykhno with the Course of Endoscopy and Endosurgery; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; doc.popovae@mail.ru Merzlikin Nikolay Vasilyevich Dr.Med.Sc, Professor, the Head of the Department of Surgical Diseases; Siberian State Medical University, Tomsk.; nikolai_merzlikin@mail.ru Pozdnyakov Artem Arkadyevich Cand. Med.Sc, Associate Professor of the Department and Clinic of Surgical Diseases named after Professor A. M. Dykhno with the Course of Endoscopy and Endosurgery; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; artem-ark@yandex.ru Sled Olga Nikolaevna Surgeon of the Surgical Department; Municipal Clinical Hospital № 20 named after I. S. Berzon, Krasnoyarsk; o.sled@bk.ru Annotation The aim of the research. To analyze remote of surgical treatment of patients with formed pancreatic cysts. Materials and methods. Up to 12 yearswere studied the results of treatment of 66 patients, was evaluated the recurrence rate, guality of life (using the SF-36), the function of the pancreas. Results. The best remote results are indicated afterradical surgery performed forpancreatic cysts. Conclusion. Application of resection and implementation of duodenum preserving operations improves the guality of life and social adaptation of patients. Keywords: pancreas, pancreatic cysts, surgical treatment Reference List: 1. Grishin I.N., Grits V.N., Lagodich S.N. Cysts, pancreatic fistulas and its complications. Minsk: Your. School, 2009.-272 p. 2. Danilov M.V., Fyodorov V.D. Surgery of the pancreas. M.: Medicine, 1995. 509 p. 3. Kurygin A.A., Nechaev E.A., Smirnov A.D. Surgical treatment of pancreatic cysts. SPb.: Hippocrates, 1996. 144 p. 4. Merzlikin N.V., Brazhnikova N.A., Tskhai V.B., Klino-vitskiy I.Yu., Komkova T.B., Sotnikov A.A. Yaroshkina T.N., ShtofinS.G., Sled N.Yu. Pancreatitis. M.:GEOTAR - Media, 2014.-528 p. 5. Paklina O.V., Chekmaryova LA., Setdikova G.R., Ni-kitin P.N., Shabunin A.V., Bedin V.V., Tavobiloa M.M. Nerve damage in chronic pancreatitis // Annals of Surgical Hepato-logy. 2011. №3. P. 95-101. 6. Pervova O.V., Vinnick Yu.S., Cherdantsev D.V., Titova N.M. Features of antihypoxic cytoflavin therapy in the treatment of destructive pancreatitis // Siberian Medical Review. 2012. № 3. P. 23-27. 7. Sukhorukov A.M., Popov A.E., Sled N.Yu., Popov S.A., Chernykh A.I. Clinical aspects of preventive measures to prevent septic complications of a destructive pancreatitis // Siberian Medical Review. 2014. № 87 (3). P. 55-58. 8. Shalimov A.A., Grubnik V.V., Gorowitz D., Zaychuk A.I., Tkachenko A.A. Chronic pancreatitis. Current concepts of the pathogenesis, diagnosis and treatment. Kiev: Health, 2000.-255 p. 9. Shchastny A.T. Pseudocyst of the pancreas: diagnosis and treatment // Surgery News. 2009. № 17 (1). P. 143-156. 10. Apostolou C, Kriger J., Bornman P. Pancreatic pseudocysts // South African Journal of Science. 2006. Vol 44, №4.-P. 148-155. 11. D'HaeseJ.G., HartelM., DemirI.E., HinzlJ., Btrgmann F., Buchler M.W., Friess H., Ceyhan G.O. Pain sensation in pancreatic diseases is not uniform: The different facets of pancreatic pain//World J Gastroenterol. 2014. Vol.20, №27. P.9154-9161. 12. Nuno-Guzman C, Arroniz-Jauregui J., Gomez-Ontiveros J., Hernandez-Estrada H., Estrada-Castaneda H., Araiza-Navarro J., Esparza-Arias N. Recurrent pancreatic pseudosyst diagnosed 9 years after initial surgical drainage // Journal of the pancreas (JOP). 2013. Vol. 12, № 3. P. 274-278. 13. Schlosser W., Siech M., H.G. Beger H.G. Pseudocyst treatment in chronic pancreatitis - surgical treatment of the underlying disease increases the long-term success // Dig. Sug. 2005. № 22. P. 340-345. 14. Wang., Liu X., Wang S., Ge N. Guo J., Liu W., Sun S., Stent displacement in endoscopic pancreatic pseudocyst drainage and endoscopic management // World J. Gastroenterol. 2015. Vol. 21, № 7. P. 2249-2253. 15. Zuleta M. Endoscopic management of pancreatic pseudocysts // Rev Col Gastroen. 2013. Vol. 28, № 3. P. 183-190. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25661 Yegorova A.T., Glebova T.K., Maiseenko D.A., Shaposhnikova E.V. Pyoinflammatory complications in obstetric practice according to the materials of the regional clinical hospital of Krasnoyarsk Pages: 47-51 . DOI 10.20333/25000136-2015-4-47-51 Authors Yegorova Antonina Timofeyema Dr.Med.Sc, Professor, Head of the Department of Obstetrics and Gynecology of the Institute of Post-Diploma Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; fetus@krasgma.ru Glebova Tatyana Konstantinovna Cand.Med.Sc, Associate Professor of the Department of Obstetrics and Gynecology of the Institute of Post-Diploma Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; glebova-tk@ya.ru Maiseenko Dmitrii Aleksandrovich Cand.Med.Sc, Associate Professor of the Department of Obstetrics and Gynecology of the Institute of Post-Diploma Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; dmitrij.maiseenko@pochta.ru Shaposhnikova Ekaterina Viktorovna Cand. Med.Sc, Associate Professor of the Department of Obstetrics and Gynecology of the Institute of Post-Diploma Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; catrina@hotbox.ru Annotation The aim of the research. To conduct comparative analysis of pyoinflammatory complications after cesarean section in puerperas in a hospital of the third level (Krasnoyarsk regional clinical hospital) for the period 2004-2005 and 2012-2013. Materials and methods. It was done the retrospective analysis of 80 cases of pyoinflammatory complications after cesarean section. All patients were divided into two clinical groups: the main group consisted of 30 puerperas, were under observation and treated in the period from 2012 - 2013, the comparison group - 50 puerperas treated between 2004 - 2005. Results. The most freguent pyoinflammatory complications of postpartum period were: acute endometritis, metroendometritis, insolvency and festering stitches on the anterior abdominal wall. With regard to complications of postpartum period the average term to transport to the hospital of the third level in patients of the main group was 4,3 ± 0,3 days, and in the comparison group 7,0 ± 0,1 day (r<0,001). This fact indicates the early diagnosis of septic complications in the initial stages of the main group of the patients. Conclusion. Currently it continues to be the underestimation of the severity of the puerperants state and belated transporting to a multiprofile hospital that exacerbates the postpartum period, leading to the development of severe complications, increasing the percentage of organ removing operations. Keywords: postpartum period, purulent-septic diseases, multiprofile hospital Reference List: 1. Egorova A.T., Tutynina O.V., Vinogradov K.A. The structure of the causes of the late maternal mortality in the Krasnoyarsk Region in 2000-2007 // Medical Almanac. 2011.-№6(19). P. 12-14. 2. Clinical guidelines. Obstetrics and Gynecology. 4th ed., Rev. and ext. / ed. V.N. Serov, G.T. Sukhikh. M.: GEOTAR Media. P. 545-607. 3. Podolyan O.F., Tsaregorodtseva M.V., Sedaya L.V. Clinical aspects of local therapy of postpartum endometritis //EeffectivePharmacotherapy. 2014. Vol.38. P.34-39. 4. Slepneva G.Z., Khomenko N.V., Yelizaryeva T.Yu, Sokolovskaya V.K. Informational Letter «Development of the Service of motherhood and childhood. Organization of obstetric care in the Krasnoyarsk Region. Year 2013.» - 61p. 5. Sukhikh G.T., Trofimov D.Yu., Burmenskaya O.V., Bayramova G.R., Nepsha O.S., Donnikov A.E. Durinyan E.R., Biryukova A.M. Profile mRNA gene expression of cytokines in the vaginal smears of women of reproductive age at non-specific vaginitis bacterial vaginosis // Obstetrics and Gynecology. 2011.-№7. P. 33-38. 6. Chechenina A.A., Polukarov A.N., Vlasenko A.E., Chechenin G.I. A look to the abdominal method of delivery through the prism of inflammatory complications in postpartum women // Mother and Child in the Kuzbass. 2014. №4. P.41-47. 7. Order of the Ministry of Health of the Krasnoyarsk Territory dated 30.07.2013 № 387 «Organization of obstetric-gynecology care in the Krasnoyarsk Region.» 8. Order of Ministry of Health of the Russian Federation dated 01.11.2012 № 572n «On approval the procedure of medical care on the profile of» Obstetrics and Gynecology (except for assisted reproductive technologies). Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25642 Zatonskaya E.V., Matyushin G.V., Gogolashvili N.H., Novgorodtseva N.N., Shul'min A.V. Frequency of heterotopic arrhythmia in the adult population of zapolyarye Pages: 52-56 . DOI 10.20333/25000136-2015-4-52-56 Authors Zatonskaya Elena Vladimirovna Postgraduate Student of the Department of Cardiology and Functional Diagnostics; Head of the Department of Functional Diagnostics; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; evzatonskaya@mail.ru Matyushin Gennady Vasilievich Doctor of Medical Sciences, Professor, Head of the Department of Cardiology and Functional Diagnostics; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; matyushinl@yandex.ru Gogolashvili Nicholay Hamletovich Doctor of Medical Sciences, Professor; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; gng1963@mail.ru Novgorodtseva Natalia Nikolaevna Cand.Med.Sc, Senior Researcher of the Cardiology Department; Research Institute of Medical Problems of the North, Russia; gng1963@mail.ru Shul'min Audrey Vladimirovich Candidate of Medical Sciences, Associate Professor, Head of Department of Public Health and Health Care; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; аndreyshumn@gmail.com Annotation he aim of the research. To study the structure and freguency of heterotopic cardiac arrhythmias (LDCs) inthepopulation of Zapolyarye. Materials and methods. Were examined 348 people of both sexes aged 20 years and older, randomly selected. To detect arrhythmias were used ECG and Holier ECG monitoring. Results. The most freguently were detected supraventricular arrhythmias, rarely - ventricular extrasystole, short episodes of supraventricular tachycardia (SVT), and a combination of various arrhythmias. Conclusion. In the adult population of Zapolyarye heterotopic LDCs are very common, the prevalence is increasing with the age. Keywords: cardiac arrhythmias, population, ECG, Holier monitoring Reference List: 1. Gogolashvili N.G., Novgorodtseva N.Ya., Polikarpov L.S., Karpov R.S. The freguency of cardiac arrhythmias in the population of the agricultural population of Krasnoyarsk region //Therapeutic Archive. 2004. № 1. P. 41-44. 2. Keiko O.I., Gerok D.V.,Gilyarov M.Yu., Novikova N.A., Sedov V.P. Clinical and echocardiographic predictors of recurrence of atrial fibrillation and flutter after electrical cardioversion // Bulletin of Arrhythmology. 2011. № 65. P. 63-67. 3. Kushakovskiy M.S. Cardiac arrhythmias. St. Petersburg.: «Foliant», 2007. 672 p. 4. Nikulina S.Y., Chernova A.A., Tretyakova S.S., Marilovtseva О .V., Bazarova A. S. The role of single nucleotide polymorphisms SCN10A in the development of cardiovascular diseases // Siberian Medical Review. 2014. № 2. P. 10-17. 5. TatarskiyB.A., SerdechnayaE.V., KazakevitchE.V. The freguence and prevalence of atrial fibrillation // Doctor. 2008. №7. P.78-90. 6. Shkol'nikova M.A., Shubik Yu.V., Shal'nova V.M., Shkol'nikov V.M., Vaupel' D. Cardiac arrhythmias in the elderly, and their association with the characteristics of health and mortality // Herald Arrhythmology. 2007. № 49. P. 5-13. 7. Ezzati M., Lopez A., Rodgers A., Hoorn S., Murray Ch., and the Comparative Risk Assessment Collaborating Group. Selected major risk factors and global and regional burden of disease//Lancet. 2002. Vol.360. P. 1347-1360. 8. Fleg J.L., Kennedy H.L. Cardiac Arrhythmias in a Healthy Elderly Population. Detection by 24-hour Ambulatory Electrocardiography // Chest. 1982. Vol. 83. P. 302-307. 9. Friberg L., Hammar N., Pettersson H., Rosengvist M. Increased mortality in paroxysmal atrial fibrillation: report from the Stockholm Cohort-Study of Atrial Fibrillation (SCAF) // Eur. Heart J. 2007. Vol. 28. P. 2346-2353. 10. Iwahana H., Ishikawa S., Ishikawa J., Kabutoya Т., Kayaba K., Gotoh Т., Kajii E. Atrial fibrillation is a major risk factor for stroke, especially in women: the Jichi Medical School cohort study // J. Epidemiol. 2011. Vol. 21. P. 95-101. 11. Lock N.S., Lau C.P. Prevalence of palpitation, cardiac arrhythmias and their associated risk factors in ambulant elderly //Int. J. Cardiol. 1996. Vol.54. P. 231-236. 12. Lown В., Calvert A., Armington R. Monitoring for serious arrhythmias and high risk sudden death // Circulation. 1975. Vol.52.-P. 189-198. 13. Manolio Т., Furberg C, Rautaharju P. Cardiac arrhythmias on 24-h ambulatory electrocardiography in older women and men: the Cardiovascular Health Study //JACC. 1994.-Vol.23. P. 916-925. 14. Murakoshi N., Aonuma K. Epidemiology of arrhythmias and sudden cardiac death in Asia // Circ. J. 2013. Vol. 77. P. 2419-2431. 15. Renate B. Schnabel R.D., Wilde S., Wild P.S., Munzel Т., Blankenberg S. Atrial Fibrillation: Its Prevalence and Risk Factor Profile in the German General Population // Dtsch. Arztebl. Int. 2012. Vol. 109. P. 293-299. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25641 Popova O.M., Sokolovskaya M.V., Buyankina R.G. Determing the level of the maturity at sustainable development of educational institution Pages: 57-60 . DOI 10.20333/25000136-2015-4-57-60 Authors Popova Oksana Mikhaeloma Employment manager of Institute of Postdegree Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; diman_abatak@mail.ru Sokolovskaya Marina Vladimirovna the Teacher of the highest gualification category, the Specialist in QMS of Quality Management Department; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; sokolovskaya-marina@yandex.ru Buyankina Rimma Gennadievna Cand.Med.Sc, Associate Professor of Department of Dentistry Clinics, Institute of Post-diploma Education and Advanced Training, the Head of Quality Management Department; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; buyankinar@mail.ru Annotation The aim of the research. Development of maturity matrix of sustainable development and to determination the level of maturity of sustainable development of the educational organization. Materials and methods. We used the standard COSTR 54598.1-2011. To achieve the aim of the research were used the following methods: expert assessments method, comparative analysis. Results. It was developed a matrix to determine the level of maturity of the sustainable development of the educational organization based on the basic principles of sustainable development GOSTR 54598.1-2011 upon which was conducted the expert evaluation of the level of maturity of sustainable development at the College of Pharmacy, Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky, Ministry of Health, RF. Conclusion. The developed maturity matrix for sustainable development for the educational organization, based on the principles of sustainable development, will be the basis for the development and implementation of a system of interaction with stakeholders and the key to success in achieving the sustainable development of the educational organization. Keywords: integrated management system, educational organization, the standard GOSTR 54598.1-2011, sustainable development, the stakeholders Reference List: 1. Belov V.V. The system of assessment for education quality//Higher education in Russia. 2002. № 1. P. 44-49. 2. COST R 54598.1 2011 Management of the organization. Guide for the Sustainable Development. Enter. 2011-12-07. M.: «Standartinform», 2012. 12 p. 3. COST ISO 9001-2011. The quality management system. Requirements. Enter. 01/01/2013. M.: «Standartinform», 2012.-28 p. 4. COST R ISO 9004-2010. Management for the sustained success of the organization. An approach based on the quality management. Enter. 2011-06-01. M.: «Standartinform», 2011.-40 p. 5. PopovaO.M. SokolovskayaM.V., BuyankinaR.G. Simulation of an integrated management system of educational organization based on the principles of sustainable development // Siberian Medical Review. 2014. № 5. P. 94-99. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25466 Reshetnikov V.A., Korshever N.G., Dorovskaya A.I. Regularities of career growth of doctors in medical organizations Pages: 61-66 . DOI 10.20333/25000136-2015-4-61-66 Authors Reshetnikov Vladimir Anatolievich Doctor of Medical Science, Professor, Head of the Department for Healthcare and Public Health; I.M. Sechenov First Moscow State Medical University; resh1960@mail.ru Korshever Natan Grigorievich Doctor of Medical Science, Professor, Department of Organization of Healthcare, Public Health and Medical Law; Saratov State Medical University named after V.I. Razumovsky; korshever@bk.ru Dorovskaya Anastasia Igorevna Assistant of Department of Organization of Healthcare, Public Health and Medical Law; Saratov State Medical University named after V.I. Razumovsky; stushaspa@yandex.ru Annotation The purpose of work. Research of the career for medical staff in medical institutions. Materials and methods. It was conducted an anonymous survey of 285 health care managers and 68 physicians-clinicians. Results. It was established the dynamics career, its aim, contributing and impeding factors. Doctors are divided by types and model types of career, strategies variants of behavior in the new position. It was done the analysis of the characteristics of the medical staff, depending on the position. Conclusion. These data allows to consider the issues of optimization of the process. Keywords: career, medical organization Reference List: 1. Gabrielyan A.R., Chernyshev A.V. The need to create a system of management the business career in multidisciplinary health care facility // Bulletin of Tambov University. Series: Natural and Technical Sciences. 2013. Vol. 18, №6(2). P. 3342-3343. 2. Yerugina M.V., Korshever N.G., Zavalyova E.V. Management adaptation of graduates of medical schools to the conditions of an independent professional activity: research, evaluation, optimization. Saratov: Publishing House of the SSMU,2014. 150 p. 3. Manerova O.A. Professional growth and career in healthcare: priorities and problems // Medical Technology. Evaluation and selection. 2011. №2. P. 77-83. 4. Radaev V.A. Expert opinions on the university education // Sociological Researches. 1994. Vol. 315, № 12. P. 51-52. 5. Reshetnikov V.A., Skvirskaya G.P., Syrtsova L.E., Kosagovskaya I.I., Boyarskiy S.G. Conceptual approaches to training the specialists in the field of health management // Healthcare of the Russian Federation. 2013. № 6. P. 9-14. 6. TrifonovaN.Yu., Gabrielyan A. R. Butrina V.I. Managing a business career of multidisciplinary hospital at the present stage // Clinical Experience of Twenties. 2013. Vol. 4, №4(20).-P. 63-66. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25461 Kapitonov V.F., Vitkin A.S., Shurova O.A. Socio-economic condition of young families and its relationship with health of children and parents Pages: 67-71 . DOI 10.20333/25000136-2015-4-67-71 Authors Kapitonov Vladimir Fedorovich Doctor of Medical Science, Professor of the Department for Health Care Management, Institute of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Vkapit5@yandex.ru Vitkin Artem Sergeyevich Applicant for an academic degree of the Department for Health Care Management, Institute of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; vitkin@ymail.com Shurova Oksana Amrikhudovna Postgraduate Student, of the Department for Health Care Management, Institute of Postgraduate Education; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; shurovao@list.ru Annotation The aim of the research. To assess the dental and physical health of children and parents in young families, depending on the socio-economic status of their families. Materials and methods. The study socio-economic status was conducted by the sociological survey of 421 mothers. Analysis of health was conducted by direct examination and study of the medical data of 536 preschool children and 779 adult family members. Results. It was determined a high proportion of children and parents, having chronic medical and dental pathology, often with family predisposition to certain diseases. Conclusion. We didn't find relationship between socio-economic factors and chronic somatic diseases, that is confirmed by the low index of correlation (p = 0,16, p = 0,001), but was revealed high level of correlation (p = 0,62, p = 0,01) between the social factors and dental disease in children and adults in young families. Keywords: socio-economic factors, somatic and dental pathology, young families Reference List: 1. Artyukhov LP., Kapitonov V.F., Novikov O.M. Family Medicine: regularities of formation the health of children in agricultural areas (prospective cohort study). Novosibirsk: Nauka,2010. 296 p. 2. Vusataya E.V., Dremalov B.N., Krasnikova O.P., Niga-mova K.I., Chulochnikova E.N. Medico-social characteristics of preschool children according to the socio-sanitary inspection // Bulletin of New Medical Technologies. 2011. № 2. P. 498-499. 3. Izmestyeva O.V. Medico-biological and socio-hygienic factors affecting to the health of children // The Doctor-Postgraduate Student. 2011. №5.4. P. 570-575. 4. Leontyev V.K., Kisel'nikova L.P. Children's dentistry: national guide. M., 2010. P. 367-389. 5. Mashina N.S., Galaktionova M.Yu. Health status of infants and its determining factors // Siberian Medical Review. 2015. № 2. P. 26-31. 6. Resolution of the Government of the Russian Federation «On the main directions of the state youth policy in the Russian Federation» dated 03.06.1993 № 5090-1. 7. Resolution of the Government of the Russian Federation «On additional measures for the implementation of the Federal Target Program» Housing" for 2002 - 2010" dated December 31, 2005 №865. 8. Strel'chenko O.V., Chernyshov V.M., Mingazov I.F. Key health indicators of population and healthcare in the Siberian Federal District in 2013 (Release 13). Novosibirsk, 2014.-298 p. 9. Shulmin A.V., Dobretsova E.A., Burgard Yu.V., Keush V.M. Medical and social characteristics of young family in contemporary conditions // Siberian medical review. 2014. № 5. P.28-35. 10. Acharya S., Bhat P.V., Acharya S. Factors affecting oral health-related guality of life among pregnant women // Int. J. Dent Hyg. 2009. № 7. P. 102-107. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25460 Tsybulskay N.Y., Harkov E.I., Pushkareva Y.I., Akhmedova E.Y. Case of noncoronary myocardial necrosis in a young woman with relapse of cervical cancer Pages: 71-73 . DOI 10.20333/25000136-2015-4-71-73 Authors Tsybulskay Nataliya Yurievna Cand.Med.Sc, Assistant of the Department of Internal Diseases Propaedeutics and Therapy; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; solna33@yandex.ru Harkov Evgeny Ivanovich Dr.Med.Sc, Professor, Head of the Department of Internal Diseases Propaedeutics and Therapy; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Harkov-50@mail.ru Pushkareva Yulia Ivanovna Cardiologist; Ambulance Hospital named after N.S. Karpovich; myJul@bk.ru Akhmedova Elvira Yuryevna Cardiologist; Ambulance Hospital named after N.S. Karpovich; elya-ax@mail.ru Annotation The article presents a case of noncoronary myocardial necrosis in a young woman with undiagnosed relapse of cervical cancer. The cause of necrosis - development of trombophilitic state, have provoked by cancer. Keywords: noncoronary myocardial necrosis, thrombophilia in malignant tumors Reference List: 1. Somonova O.V. Hemostatic disorders in cancer patients: state oi the problem (review) // Bulletin RCRC named after N.N. Blokhin. 2006. Vol. 17, № 1. P. 38-42. 2. Sushkevich G.N. Pathogenesis and laboratory diagnosis oi hemostatic disorders in thrombophilia oi different genesis //LaboratoryMedicine. 2009. № 10. P. 11-22. 3. Shilova A.N., Barkagyan Z.S. Recent data on the ireguency and pathogenesis oi oncothrombosis // Thrombosis, HemostasisandRheology. 2006. Vol. 25, № 1. P. 6-15. 4. Falanga A., Marchetti M., Vignoli A. Coagulation and cancer: biological and clinical aspects // Journal Thromb Haemost. 2013. №. 11. P. 223-233. 5.KawanoN.,YamaguchiK., NikiT., YamamotoT., Iwase Т., TaketaniY., IseT., YamadaH., SoekiT., WakatsukiT., KawanoK., KakutaniA., SataM. Two cases oi acute myocardial iniarction during combined chemotherapy in young patients with testicular cancer // Journal oi Cardiology Cases. 2013. Vol. 7, № 6. P. 176-180. 6. Thygesen K., AlpertJ., Jaffe A., Simoons M., Chairman В., White H. et al. Третье универсальное определение инфаркта миокарда // Российский кардиологический журнал. 2013. Т. 100, № 2, Приложение 1. С. 1-16. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25460 Tskhay V.B., Kolesnichenko A.P., Garber J.G., Glizina J.N., Raspopin J.S., Yametov P.K., Reodko S.V., Schneiderman E.V. Spontaneous rupture of uterus at scar after cesarean section combined with ingrowth of placenta Pages: 74-78 . DOI 10.20333/25000136-2015-4-74-78 Authors Tskhay Vitaly Borisovich Dr. Med. Sc, Professor, Head of the Department of Perinatology, Obstetrics and Gynecology; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; tchai@yandex.ru Kolesnichenko Anatoliy Pavlovich Dr. Med. Sc, Professor of the Department of Anesthesiology and Intensive Care; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; gritsan67@mail.ru Garber Julia G Deputy Head of Obstetrics and Gynecology Care; Krasnoyarsk Regional Center of Maternal and Child Health; kdb@kdb.kasmed.ru Glizina Julia Nicolayevna Cand.Med.Sc, Head of the Maternity Department; Assistant of the Department of Perinatology, Obstetrics and Gynecology; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; glizinajulia@mail.ru Raspopin Juriy Svyatoslavovich Head oflCUThe Center of Maternal and Child Health; Center of Maternal and Child Health; oar24@mail.ru Yametov Pavel Konstantinovich Assistant of the department of Perinatology, Obstetrics and Gynecology; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; rurwap@mail.ru Reodko Svetlana Victorovna Obstetrician-gynecologist; The Center of Maternal and child health; kkkc@pericentr.ru Schneiderman Eugene Vadimovich Obstetrician-gynecologist; The Center of Maternal and child health; kkkc@pericentr.ru Annotation Caesarean section is the most commonly performed surgical procedure in women of childbearing age. The freguency of cesarean section has been steadily increasing throughout the world and, conseguently, increases the number of complications associated with this operation. One of these complications, which can lead to critical and sometimes fatal complication is rupture of the uterus due to insolvency of the uterine scar after a previous cesarean. This article describes a rare case of uterine rupture in women in the second trimester of pregnancy, which occurred as a result of the germination of the placenta in the postoperative scar after cesarean corporal. Keywords: cesarean section, uterine rupture, placental ingrowth Reference List: 1. Baskett T.F., Kalder E.A., Arulkumaran S. Surgical obstetrics Manro Kerra / Ed. M.A. Kurtser. Trans. P.I. Medvedeva. M.: Rid Elsiver, 2010. P. 392. 2. Buyanova S.N., Schukina N.A., Chechneva M.A. Modern methods of diagnostics of suture failure or cicatrical tussue on uterus after Cesarean section // Russian vestnik of obstetrics and gynecology. 2013. № 1. P. 73-77. 3. Tshaj V.B., Glyzina Yu. N. Dudina A. Yu. Spontaneous rupture of uterus in full-term pregnancy // Obstetrics and gynecology. 2013. №5. P. 103-106. 4. Chen F.P. Term delivery after repair of a uterine rupture during the second trimester in a previously unscarred uterus: a case report // J. Reprod. Med. 2007. Vol. 52. P. 981-983. 5. Dew L, Harris S., Yost N., Magee K., dePrisco G. Second trimester placenta percreta presenting as acute abdomen // Proc (Bayl UnivMed Cent). 2015. Vol. 28. P. 38-40. 6. Jia L.Y., Meng W.Y., Ma H.H., Tian J. Clinical analysis of uterine rupture during pregnancy // Zhonghua Yi Xue Za Zhi. 2013. Vol. 93. P. 2674-2676. 7. Kazandi M. Placenta percreta: report of two cases and review of the literature // Clin. Exp. Obstet. Gynecol. 2003. Vol. 30. P. 70-72. 8. KinoshitaT., OgawaK.,YasumizuT., KatoJ.Spontaneous rupture of the uterus due to placenta percreta at 25-weeks' gestation: a case report//J. Obstet. Gynaecol. Res. 1996. Vol.22.-P. 125-128. 9. LeMaire W.J., Louisy C, Dalessandri K., Muschen-heim F. Placenta percreta with spontaneous rupture of an unscarred uterus in the second trimester // Obstet Gynecol. 2001. Vol.98. P. 927-929. 10. Palacios-Jaraguemada J.M., Fiorillo A., von Petery F., Colaci D., Leguizamon G. Uterine repair and successful pregnancy after myometrial and placental rupture with massive haemoperitoneum//BJOG. 2009. Vol. 116. P. 456-460. 11. Roeters A.E., Oudijk M.A., Heydanus R., Bruinse H.W. Pregnancy outcome after intra-abdominal bleeding due to placenta percreta at 14 weeks of gestation // Obstet. Gynecol. 2007. Vol. 109. P. 574-576. 12. Sentilhes L., Vayssiere C, Beucher G., Deneux-Tharaux C, Deruelle P., Diemunsch P., Gallot D., Haumonte J.В., Heimann S., Kayem G., Lopez E., Parant O., Schmitz Т., SellierY., Rozenberg P., d'Ercole С Delivery for women with a previous cesarean: guidelines for clinical practice from the French College of Gynecologists and Obstetricians (CNGOF) // Eur. J. Obstet. Gynecol. Reprod. Biol. 2013. № 1. P. 25-32. 13. Sugawara Т., Ogawa M, Tanaka T. Repair of Uterine Rupture during Second Trimester Leading to Successful Pregnancy Outcome: Case Study and Literature's Review // AJP Rep. 2014. Vol. 4. P. 9-12. 14. VyrdalC.D., KirkegaardM.fi, Nielsen V., Hoj L. Uterine rupture caused by placenta percreta in the first half of the pregnancy// Ugeskr. Laeger. 2014. № 2. P. 101-184. 15. Wang L.M., Wang P.H., Chen C.L., Au H.K., Yen Y.K., Liu W.M. Uterine preservation in a woman with spontaneous uterine rupture secondary to placenta percreta on the posterior wall: a case report // J. Obstet. Gynaecol. Res. 2009. Vol. 35. P. 379-384. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25317 Konovalov P.P., Arsentev O.V., Buyanov A.L., Bekmurazov S.M. The use of biological weapons -realities of the contemporary world Pages: 79-84 . DOI 10.20333/25000136-2015-4-79-84 Authors Konovalov Pyotr Petrovich Cand.Med.Sc, Colonel of Medical Service; Head of the Federal state public institutions «354th Military Clinical Hospital»; OWKG-354@yandex.ru Arsentev Oleg Victorovich Deputy Head; Federal state public institutions 354th Military Clinical Hospital the Ministry of Defense of the Ru; OWKG-354@yandex.ru Buyanov Alexander Lvovich Deputy Head; Federal state public institutions «354th Military Clinical Hospital» the Ministry of Defense of the; OWKG-354@yandex.ru Bekmurazov Sergey Mukhtarovich Colonel of Medical Service; Head of the Federal state public institutions 425th Military Hospital the Ministry of Defense of the; f8-owkg-354@yandex.ru Annotation The problem of anti-terrorist protection from biological weapons is extremely actual for the contemporary Russian Federation. In order to counter bioterrorism and according to the decision of the Federal Anti-Terrorist Commission it was adopted the concept of anti-terrorist activities of federal executive bodies in the field of environmental protection and public health. Keywords: weapons of mass destruction, bioterrorism, biological weapons Reference List: 1. Abarenkov V.P., Krasulin B.P. Disarmament. M.: International relations, 1988. 336 p. 2. Antropova A.E. Biological weapons - a threat to international security//Professional. 2006. № 1. P. 44-45. 3. Belous V V Assessment of the threat of mass destruction weapons for terrorist purposes // Disarmament and Security: 2001-2002. International Security: new threats of the new millennium / edited. AG Arbatov. M.: Nauka, 2003. P. 37-57. 4. Bobylov Yu.A. Genetic bomb. Secret bioterrorism scenarios. M.White Alva, 2006. 240 p. 5. Bobylov Yu.A. New biological weapons: change of the paradigm in Russian geopolitical thinking // National Security and Geopolitics of Russia. 2005. № 3-4. P. 14-22. 6. Bondarenko G.A., Sychev A.P. Biological weapons. M., 2003. 31 p. 7. Evstigneev V.I., Ryabikhin L.F., Scherbakov G.Ya. Problems of biological safety and the fight against bioterrorism // Diplomatic Yearbook 2003 - M.: Science Book, 2004. P. 61-71. 8. Illarionov S.I. The terror and anti-terror in the modern world order. M.: RIC ProfEko, 2003. 592 p. 9. Kosachev K.I. The concept of development of interna-tionallaw in the fight against nuclear terrorism: Author. Dis.... Cand. Jur. Sciences. M., 2003. 27 p. 10. Kotlyar V.S. Ways of strengthening the Convention on Biological Weapons // Actual international legal and humanitarian problems: Collection of Articles. M, 2003. Issue IV. P. 257-276. 11. LyakhovE.G. Policy of terrorism policy of violence and aggression. M.: International relations, 1987. 184 p. 12. LyakhovE.G., Popov A. V. Terrorism: national, regional and international controls. Rostov-on-Don Ruy Russian Interior Ministry, 1999. 436 p. 13. Nemits V.F. Biological terrorism and possible ways of its prevention // Guard: service, technical means, the economy. 2006. №3. P. 80-83. 14. Nemits V.F., Antropova A.E. Problems of prevention of terrorist acts with the use of biological weapons //«Black Holes» in the Russian legislation. 2006. №4. P. 417-422. 15. Ensuring of biological, chemical and toxic radiation safety at terrorist acts / Ed. Academician RAMS, Professor G.G. Onishchenko. M.: MP Hygiene, 2005. 431 p. 16. Onishchenko G.G., Sandakhchiev L.S., Netyosov S.V., Martynyuk R.A. Bioterrorism: National and global threat // Bulletin of the Russian Academy of Sciences. 2003. Vol. 73, №3. P. 195-204. 17. Onishchenko G.G. Counteraction to bioterrorism: A Strategy for the National Health//Vaccination. 2002. № 3. P. 4-5. 18. Pal'tsev M.A. Biological weapons is a problem of national security of Russia // National Security. 2002. № 1-2. P. 4649. 19. Sandakhchiev L.S., Martynyuk R.A. The need for international cooperation for the success of the fight against infectious diseases and bioterrorism // Chemical and Biological Safety. 2004. № 1-2. P. 3-8. 20. Sevostyanov V.V. Terrorism on the self-repayment // Military-Industrial Courier. 2007. № 10. P. 25-37. 21. Simonov A.E. International legal aspects of the fight against bioterrorism: Author. Dis.... Cand. Jur. Sciences. M., 2007. 21 p. 22. Terrorism and counter-terrorism in the modern world: analytical materials, documents, glossary / Ed. O.A. Kolo-bov. M.,2003. 480 p. 23. Trebin M.P. Terrorism in the XXI century. Minsk: Harvest, 2004.-816 p. 24. Hlobustov O.M. Some concepts and terms in the fight against modern terrorism // Russian investigator. 2006. №5.-P. 12-15. 25. Shubin A.V. Russia and the World in 2020. The country's future in a changing global environment. Report of the National Intelligence Council of the US «The contours of the future world.» - M.: Europe, 2005. 219 p. 26. Shcherbakov G.B. The sources and the main threats to the national security // Nuclear Proliferation. 2003. Vol. 47. P. 50-59. 27. Frist W.H. When Every Moment Counts: What You Need to Know about Bioterrorism from the Senates only Doctor. Rowman & Littlefield, 2002. 192 p. 28. Henderson D. A., Inglesby T. V. Bioterrorism: Guidelines for Medical and Public Health Management. American Medical Association, 2002. 244 p. 29. Inglesby T. V. Bioterrorist Threats: What the Infectious Disease Community Should Know about Anthrax and Plague // Emerging Infections. American Society for Microbiology Press, 2001.-P. 223-234. 30. Kaufmann A.F., Meltzer M.I., Schmid G.P. The Economic Impact of a Bioterrorist Attack: Are Prevention and Postattack Intervention Program Justifiable? // Emerging Infectious Diseases. 1997. №3. P. 83-94. 31. Mobley J.A. Biological Warfare in the Twentieth Century: Lessons from the Past, Challenges for the Future // Military Medicine. 1995. Vol. 160. P. 547-553. 32. Richards C.F., BursteinJ.L, WaecherleJ.F., HutsonH.R. Emergency Physicians and Biological Terrorism // Annals of Emergency Medicine. 1999. №. 8. P. 183-190. 33. RonL.D., KhanA.S., LillibridgeS.R.etal. Public Health Assessment of Potential Biological Terrorism Agents: Emerging Infectious Diseases. 2002. Vol. 8, № 2. P. 225-230. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 25288 . DOI 10.20333/25000136-2015-4-85-92 Authors Kozlov V. V. ; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; kv1v@rambler.ru Annotation The lecture discusses the clinical peculiarities of chronic adenoiditis in children. Here are submitted the contemporary criteria of the diagnosis, treatment and prevention principles, criteria of prognosis and functional outcome of the disease Keywords: chronic adenoiditis, risk factors, prognosis criteria, personalized diagnosis and treatment Reference List: 1. Bykova V.P. New arguments in supporting of organ preserving direction in the treatment of adenoids in children // Children's Otolaryngology. 2013. № 2. P. 18-22. 2. Vavilova V.P., Garashchenko T.I., Perevoshchikova N.K., Bogomilsky M.R., Grabovschiner A.Ya. Quantum therapy in complex treatment of sickly children with chronic adenoiditis. M.: MILTA-PKP-GIT, 2009. 151 p. 3. Karpova E.P., Tulupov D.A. Chronic adenoiditis in children: a manual for physicians. M.: Publishing House of the Academy of Postgraduate Education, 2009. 53 p. Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 24843 Kurtasova L.M. Review of the monograph А. A. Savchenko, M. A. Dudina, S. A. Dogadina «Features of the immunoendocrine interactions in acromegaly.» - Krasnoyarsk, 2014.-111 p. Pages: 93-95 . DOI 10.20333/25000136-2015-4-93-95 Authors Kurtasova Lyudmila Mikhailoma Dr.Med.Sc, Professor, Department of Clinical Immunology; Krasnoyrask State Medical University named after Prof. V.F. Voino-Yasenetsky; sibmed-obozrenie@yandex.ru Annotation The book contains the current aspects of integrated interactions of somatotropic function of pituitary and the immune system, as key mechanisms for the development of immune deficiency in chronic overproduction ofSTG/IGF-1, shows their role in the development of neoplasia in acromegaly. Chronic hypersecretion of growth factors in acromegaly changes subpopulation structure, chemiluminescent activity and metabolism of cells of the immune system that can be used to develop approaches to an objective assessment of the state of the immune system of patients, and in the differential treatment of cancer complications of the disease. Keywords: acromegaly, the immune system, metabolism Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 24765 . Authors Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 24748 Timoshenko V.O. Historical pages of the dental faculty of Krasnoyarsk state medical university named after professor V. F. Voino-yasenetsky Pages: 97-100 Historical pages of the dental faculty of Krasnoyarsk state medical university named after professor V. F. Voino-Нasenetsky. DOI 10.20333/25000136-2015-4-97-100 Authors Timoshenko Vera Olegovna Cand.Med.Sc, Decent, the chair of health care; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; OZiZKrasGMU@bk.ru Annotation The lecture presents data of archival documents about the establishing, the staff of the Dental Faculty of the Krasnoyarsk Medical Institute during the Great Patriotic War. Keywords: Krasnoyarsk Medical Institute, the Great Patriotic War, Dental Faculty Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 24770 Shtarik S.Y. Review of dissertation topics that were submitted in 2014 by the committee of dissertation defense for the degree of candidate of science, for the degree of doctor of science d 208.037.01 in specialty 14.01.04 - internal diseases Pages: 100-107 . Authors Shtarik S. Yu. Dr. Med. Sci.,Professor; Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; shtarik@yandex.ru Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 24738 Gorbach N.A. Review of dissertation topics that were submitted in 2014 by the committee of dissertation defense for the degree of candidate of science, for the degree of doctor of science d 208.037.02 in specialty 14.01.17 - neurological diseases Pages: 108-113 . Authors Gorbach N. A. Dr.Med.Sc, Professor; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; gorbn@mail.ru Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 24723 Kochetova L.V. Review of dissertation topics that were submitted in 2014 by the committee of dissertation defense for the degree of candidate of science, for the degree of doctor of science d 208.037.02 in specialty 14.01.17 - surgery Pages: 114-116 . Authors Kochetova Lyudmila Victorovna Cand.Med.Sc., Associate Professor of the chair of general surgery, Academic Secretary of the Dissertation Council D 208.037.05; Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; dissovetkrasgmu@bk.ru Comments Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10 Table 'site57.sys_comment' doesn't exist Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53 Table 'site57.sys_comment' doesn't exist Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33 Table 'site57.sys_comment' doesn't exist Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39 Table 'site57.sys_comment' doesn't exist Visits: 24706 |
Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 10
Table 'site57.sys_comment' doesn't exist
Warning: mysqli_query(): (42S02/1146): Table 'site57.sys_comment' doesn't exist in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 53
Table 'site57.sys_comment' doesn't exist
Warning: mysqli_num_rows() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 33
Table 'site57.sys_comment' doesn't exist
Warning: mysqli_fetch_assoc() expects parameter 1 to be mysqli_result, bool given in /home/var/www/mirror/site/smr.krasgmu.ru/sys/phpsys/__db.php on line 39
Table 'site57.sys_comment' doesn't exist